{"id":10293,"date":"2021-06-09T11:26:44","date_gmt":"2021-06-09T18:26:44","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10293"},"modified":"2021-06-10T11:27:27","modified_gmt":"2021-06-10T18:27:27","slug":"functional-characterization-of-sars-cov-2-vaccine-elicited-antibodies-in-immunologically-nave-and-pre-immune-humans","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/09\/functional-characterization-of-sars-cov-2-vaccine-elicited-antibodies-in-immunologically-nave-and-pre-immune-humans\/","title":{"rendered":"Functional Characterization of SARS-CoV-2 Vaccine Elicited Antibodies in Immunologically Nave and Pre-Immune Humans"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> The Pfizer-BioNTech vaccine elicited higher neutralizing and anti-SARS-CoV-2 antibody binding responses in individuals with prior infection (n=32) compared to those without prior infection (n=20). The second vaccine dose did not significantly increase neutralizing or binding antibody levels in individuals with prior infection, whereas the second dose was required to induce antibody responses in nearly half of infection-na\u00efve individuals.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Forgacs et al.\u00a0(May 31, 2021). Functional Characterization of SARS-CoV-2 Vaccine Elicited <\/span><\/i> <i><span style=\"font-weight: 400\">Antibodies in Immunologically Nave and Pre-Immune Humans. Pre-print downloaded Jun 9 from <\/span><\/i> <a href=\"https:\/\/doi.org\/10.1101\/2021.05.29.445137\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.29.445137<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] The Pfizer-BioNTech vaccine elicited higher neutralizing and anti-SARS-CoV-2 antibody binding responses in individuals with prior infection (n=32) compared to those without prior infection (n=20). The second vaccine dose did not significantly increase neutralizing or binding antibody levels in individuals with prior infection, whereas the second dose was required to induce antibody responses&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/09\/functional-characterization-of-sars-cov-2-vaccine-elicited-antibodies-in-immunologically-nave-and-pre-immune-humans\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,32,33],"topic":[31],"class_list":["post-10293","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-immunity","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10293","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10293"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10293\/revisions"}],"predecessor-version":[{"id":10294,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10293\/revisions\/10294"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10293"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10293"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10293"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}