{"id":10376,"date":"2021-06-14T08:38:24","date_gmt":"2021-06-14T15:38:24","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10376"},"modified":"2021-06-16T08:39:34","modified_gmt":"2021-06-16T15:39:34","slug":"the-sars-cov-2-mrna-vaccine-breakthrough-infection-phenotype-includes-significant-symptoms-live-virus-shedding-and-viral-genetic-diversity","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/14\/the-sars-cov-2-mrna-vaccine-breakthrough-infection-phenotype-includes-significant-symptoms-live-virus-shedding-and-viral-genetic-diversity\/","title":{"rendered":"The SARS-CoV-2 MRNA Vaccine Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A study of 24 breakthrough SARS-CoV-2 infections among fully vaccinated US Military Health System beneficiaries indicated that most infections (67%) occurred among those without comorbid conditions, 57% reported close contact with a COVID-19 case in the past month, and no case of breakthrough infection resulted in hospitalization. Sequencing from 10 of 13 qPCR-positive specimens indicated the presence of variants of concern or interest including B.1.1.7 (Alpha) (n=2), P.1 (Gamma) (n=1), and B.1.429 (Epsilon) (n=2) in addition to other strains not classified as variants of concern or interest, including B.1.1 (n=1), B.1.1.519 (n=1), B.1.2 (n=2), and B.1.243 (n=1).<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Pollett et al.\u00a0(June 2021). The SARS-CoV-2 MRNA Vaccine Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity. Clinical Infectious Diseases. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciab543\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1093\/cid\/ciab543<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study of 24 breakthrough SARS-CoV-2 infections among fully vaccinated US Military Health System beneficiaries indicated that most infections (67%) occurred among those without comorbid conditions, 57% reported close contact with a COVID-19 case in the past month, and no case of breakthrough infection resulted in hospitalization. Sequencing from 10 of 13 qPCR-positive specimens indicated&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/14\/the-sars-cov-2-mrna-vaccine-breakthrough-infection-phenotype-includes-significant-symptoms-live-virus-shedding-and-viral-genetic-diversity\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[222,141],"topic":[31],"class_list":["post-10376","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccine-breakthrough","tag-variant","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10376"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10376\/revisions"}],"predecessor-version":[{"id":10377,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10376\/revisions\/10377"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10376"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}