{"id":10401,"date":"2021-06-15T08:59:05","date_gmt":"2021-06-15T15:59:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10401"},"modified":"2021-06-16T08:59:55","modified_gmt":"2021-06-16T15:59:55","slug":"sars-cov-2-antibody-persistence-in-covid-19-convalescent-plasma-donors-dependency-on-assay-format-and-applicability-to-serosurveillance","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/15\/sars-cov-2-antibody-persistence-in-covid-19-convalescent-plasma-donors-dependency-on-assay-format-and-applicability-to-serosurveillance\/","title":{"rendered":"SARS-CoV -2 Antibody Persistence in COVID-19 Convalescent Plasma Donors: Dependency on Assay Format and Applicability to Serosurveillance"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">SARS-CoV-2 antibody responses were shown to increase over time in a study of plasma collected up to 63-129 days following symptom resolution from 18 patients recovered from COVID-19 when using direct double Ag-sandwich assays (Ortho Total Ig and Roche Total Ig). By contrast, measurements from indirect binding assays showed a declining antibody response. Due to their stability over time, the authors suggest using direct double sandwich assays for serosurveillance studies.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Di Germanio et al.\u00a0(June 14, 2021). SARS-CoV -2 Antibody Persistence in COVID-19 Convalescent Plasma Donors: Dependency on Assay Format and Applicability to Serosurveillance. Transfusion. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1111\/trf.16555\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1111\/trf.16555<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2 antibody responses were shown to increase over time in a study of plasma collected up to 63-129 days following symptom resolution from 18 patients recovered from COVID-19 when using direct double Ag-sandwich assays (Ortho Total Ig and Roche Total Ig). By contrast, measurements from indirect binding assays showed a declining antibody response. Due to&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/15\/sars-cov-2-antibody-persistence-in-covid-19-convalescent-plasma-donors-dependency-on-assay-format-and-applicability-to-serosurveillance\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[19],"class_list":["post-10401","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10401","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10401"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10401\/revisions"}],"predecessor-version":[{"id":10402,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10401\/revisions\/10402"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10401"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10401"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10401"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}