{"id":1093,"date":"2020-09-23T11:23:41","date_gmt":"2020-09-23T18:23:41","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1093"},"modified":"2020-09-24T11:24:55","modified_gmt":"2020-09-24T18:24:55","slug":"evaluation-of-pooled-sample-analysis-strategy-in-expediting-case-detection-in-areas-with-emerging-outbreaks-of-covid-19-a-pilot-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/23\/evaluation-of-pooled-sample-analysis-strategy-in-expediting-case-detection-in-areas-with-emerging-outbreaks-of-covid-19-a-pilot-study\/","title":{"rendered":"Evaluation of Pooled Sample Analysis Strategy in Expediting Case Detection in Areas with Emerging Outbreaks of COVID-19: A Pilot Study"},"content":{"rendered":"<ul>\n<li>Pooling 5 nasopharyngeal or oropharyngeal samples during PCR testing would offer a reduction of laboratory turn-around time by 66% and the cost of diagnosis by 68%. However, the sensitivity was compromised, with 5 of the 109 pools showing discordant results when compared with individual results. Single samples with Ct value \u00b334 were likely to be missed in the pool. The negative predictive value of qRT-PCR on pooled samples was around 96%.<\/li>\n<\/ul>\n<p>Singh et al. (Sept 22, 2020). Evaluation of Pooled Sample Analysis Strategy in Expediting Case Detection in Areas with Emerging Outbreaks of COVID-19: A Pilot Study. PLOS ONE. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0239492\">https:\/\/doi.org\/10.1371\/journal.pone.0239492<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pooling 5 nasopharyngeal or oropharyngeal samples during PCR testing would offer a reduction of laboratory turn-around time by 66% and the cost of diagnosis by 68%. However, the sensitivity was compromised, with 5 of the 109 pools showing discordant results when compared with individual results. Single samples with Ct value \u00b334 were likely to be&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/23\/evaluation-of-pooled-sample-analysis-strategy-in-expediting-case-detection-in-areas-with-emerging-outbreaks-of-covid-19-a-pilot-study\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[27],"topic":[19],"class_list":["post-1093","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1093","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1093"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1093\/revisions"}],"predecessor-version":[{"id":1094,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1093\/revisions\/1094"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1093"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1093"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}