{"id":1101,"date":"2020-09-23T11:29:15","date_gmt":"2020-09-23T18:29:15","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1101"},"modified":"2020-09-24T11:30:11","modified_gmt":"2020-09-24T18:30:11","slug":"risk-of-adverse-covid-19-outcomes-for-people-living-with-hiv-a-rapid-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/23\/risk-of-adverse-covid-19-outcomes-for-people-living-with-hiv-a-rapid-review-and-meta-analysis\/","title":{"rendered":"Risk of Adverse COVID-19 Outcomes for People Living with HIV a Rapid Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer-reviewed] Pooled results from 5 studies (median sample size 55 [IQR 35-115]) showed that people living with HIV had a 1.9-fold higher risk of COVID-19 mortality (95%CI 1.6-2.3) compared to people without HIV. Two studies reported that tenofovir-based antiretroviral therapy regimens were associated with a lower risk of adverse COVID-19 outcomes, but the associations were confounded by comorbidities. The authors suggest further research to assess the role of antiretroviral therapy regimen, degree of immunosuppression, and viral load on COVID-19 outcomes for people living with HIV in diverse settings.<\/li>\n<\/ul>\n<p>Mellor et al. (Sept 23, 2020). Risk of Adverse COVID-19 Outcomes for People Living with HIV a Rapid Review and Meta-Analysis. Pre-print downloaded Sept 23 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.22.20199661\">https:\/\/doi.org\/10.1101\/2020.09.22.20199661<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Pooled results from 5 studies (median sample size 55 [IQR 35-115]) showed that people living with HIV had a 1.9-fold higher risk of COVID-19 mortality (95%CI 1.6-2.3) compared to people without HIV. Two studies reported that tenofovir-based antiretroviral therapy regimens were associated with a lower risk of adverse COVID-19 outcomes, but the&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/23\/risk-of-adverse-covid-19-outcomes-for-people-living-with-hiv-a-rapid-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-1101","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1101"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1101\/revisions"}],"predecessor-version":[{"id":1102,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1101\/revisions\/1102"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1101"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1101"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1101"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}