{"id":1118,"date":"2020-09-24T10:17:52","date_gmt":"2020-09-24T17:17:52","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1118"},"modified":"2020-09-25T11:03:22","modified_gmt":"2020-09-25T18:03:22","slug":"decreased-mortality-in-covid-19-patients-treated-with-tocilizumab-a-rapid-systematic-review-and-meta-analysis-of-observational-studies","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/24\/decreased-mortality-in-covid-19-patients-treated-with-tocilizumab-a-rapid-systematic-review-and-meta-analysis-of-observational-studies\/","title":{"rendered":"Decreased Mortality in COVID-19 Patients Treated with Tocilizumab: A Rapid Systematic Review and Meta-Analysis of Observational Studies"},"content":{"rendered":"<ul>\n<li>Tocilizumab was associated with a lower mortality (RR:0.27, 95% CI: 0.12-0.59; risk difference 12%, 95% CI: 4.6%-20%) based on pooled data from 10 studies comprising 1358 patients with COVID-19. The number needed to treat was 11, suggesting that 1 death is prevented for every 11 patients with severe COVID-19 treated with tocilizumab. No differences in side effects were observed.<\/li>\n<\/ul>\n<p>Malgie et al. (Sept 23, 2020). Decreased Mortality in COVID-19 Patients Treated with Tocilizumab: A Rapid Systematic Review and Meta-Analysis of Observational Studies. Clinical Infectious Diseases. <a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1445\">https:\/\/doi.org\/10.1093\/cid\/ciaa1445<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tocilizumab was associated with a lower mortality (RR:0.27, 95% CI: 0.12-0.59; risk difference 12%, 95% CI: 4.6%-20%) based on pooled data from 10 studies comprising 1358 patients with COVID-19. The number needed to treat was 11, suggesting that 1 death is prevented for every 11 patients with severe COVID-19 treated with tocilizumab. No differences in&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/24\/decreased-mortality-in-covid-19-patients-treated-with-tocilizumab-a-rapid-systematic-review-and-meta-analysis-of-observational-studies\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[52,28],"topic":[19],"class_list":["post-1118","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-review","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1118"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1118\/revisions"}],"predecessor-version":[{"id":1119,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1118\/revisions\/1119"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1118"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}