{"id":1161,"date":"2020-09-25T09:43:24","date_gmt":"2020-09-25T16:43:24","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1161"},"modified":"2020-09-28T09:46:34","modified_gmt":"2020-09-28T16:46:34","slug":"safety-and-immunogenicity-of-the-ad26-cov2-s-covid-19-vaccine-candidate-interim-results-of-a-phase-1-2a-double-blind-randomized-placebo-controlled-trial","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/25\/safety-and-immunogenicity-of-the-ad26-cov2-s-covid-19-vaccine-candidate-interim-results-of-a-phase-1-2a-double-blind-randomized-placebo-controlled-trial\/","title":{"rendered":"Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate: interim results of a phase 1\/2a, double-blind, randomized, placebo-controlled trial"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer reviewed] A one-dose vaccine candidate was shown to have an acceptable safety profile and demonstrated immunogenicity. These results come from a multi-center phase 1\/2a randomized, double-blinded, placebo-controlled clinical study of the Ad26.COV2.S vaccine candidate. The vaccine platform utilizes Janssen Pharmaceutical\u2019s replication incompetent adenovirus serotype 26 (Ad26) 54 vector and includes a stabilized SARS-CoV-2 Spike (S) protein insert. The Ad26.COV2.S is the only one-dose vaccine currently entering Phase III clinical trials in the US.<\/li>\n<\/ul>\n<p>Sadoff et al. Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate: interim results of a phase 1\/2a, double-blind, randomized, placebo-controlled trial. Pre-print downloaded Sept 25 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.23.20199604\">https:\/\/doi.org\/10.1101\/2020.09.23.20199604<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed] A one-dose vaccine candidate was shown to have an acceptable safety profile and demonstrated immunogenicity. These results come from a multi-center phase 1\/2a randomized, double-blinded, placebo-controlled clinical study of the Ad26.COV2.S vaccine candidate. The vaccine platform utilizes Janssen Pharmaceutical\u2019s replication incompetent adenovirus serotype 26 (Ad26) 54 vector and includes a stabilized&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/25\/safety-and-immunogenicity-of-the-ad26-cov2-s-covid-19-vaccine-candidate-interim-results-of-a-phase-1-2a-double-blind-randomized-placebo-controlled-trial\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[33],"topic":[31],"class_list":["post-1161","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1161","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1161"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1161\/revisions"}],"predecessor-version":[{"id":1162,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1161\/revisions\/1162"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1161"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}