{"id":1255,"date":"2020-09-30T10:30:26","date_gmt":"2020-09-30T17:30:26","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1255"},"modified":"2020-10-01T10:31:47","modified_gmt":"2020-10-01T17:31:47","slug":"angiotensin-converting-enzyme-2-ace2-levels-in-relation-to-risk-factors-for-covid-19-in-two-large-cohorts-of-patients-with-atrial-fibrillation","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/30\/angiotensin-converting-enzyme-2-ace2-levels-in-relation-to-risk-factors-for-covid-19-in-two-large-cohorts-of-patients-with-atrial-fibrillation\/","title":{"rendered":"Angiotensin-Converting Enzyme 2 (ACE2) Levels in Relation to Risk Factors for COVID-19 in Two Large Cohorts of Patients with Atrial Fibrillation"},"content":{"rendered":"<ul>\n<li>Male sex, cardiovascular disease, diabetes, and biomarker indicators of biological aging were associated with higher levels of soluble angiotensin-converting enzyme 2 (sACE2) among two international cohorts of elderly patients with atrial fibrillation. Higher levels of sACE2 could reflect a higher cellular expression of ACE2, a cellular receptor by which SARS-CoV-2 enters human cells, and thus pose as higher risk for severe COVID-19 infection.<\/li>\n<\/ul>\n<p>Wallentin et al. (Sept 27, 2020). Angiotensin-Converting Enzyme 2 (ACE2) Levels in Relation to Risk Factors for COVID-19 in Two Large Cohorts of Patients with Atrial Fibrillation. European Heart Journal. <a href=\"https:\/\/doi.org\/10.1093\/eurheartj\/ehaa697\">https:\/\/doi.org\/10.1093\/eurheartj\/ehaa697<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Male sex, cardiovascular disease, diabetes, and biomarker indicators of biological aging were associated with higher levels of soluble angiotensin-converting enzyme 2 (sACE2) among two international cohorts of elderly patients with atrial fibrillation. Higher levels of sACE2 could reflect a higher cellular expression of ACE2, a cellular receptor by which SARS-CoV-2 enters human cells, and thus&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/30\/angiotensin-converting-enzyme-2-ace2-levels-in-relation-to-risk-factors-for-covid-19-in-two-large-cohorts-of-patients-with-atrial-fibrillation\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[25,75,76,28],"topic":[20],"class_list":["post-1255","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-candidate","tag-report","tag-summarize","tag-treatment","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1255"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1255\/revisions"}],"predecessor-version":[{"id":1256,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1255\/revisions\/1256"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1255"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}