{"id":1280,"date":"2020-10-01T09:24:38","date_gmt":"2020-10-01T16:24:38","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1280"},"modified":"2020-10-02T09:26:42","modified_gmt":"2020-10-02T16:26:42","slug":"recent-endemic-coronavirus-infection-is-associated-with-less-severe-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/01\/recent-endemic-coronavirus-infection-is-associated-with-less-severe-covid-19\/","title":{"rendered":"Recent Endemic Coronavirus Infection Is Associated with Less Severe COVID-19"},"content":{"rendered":"<ul>\n<li>Pre-existing immune responses against endemic human coronaviruses (eCoVs), which are etiologic agents for the &#8220;common cold\u201d that share extensive sequence homology with SARS-CoV-2, may mitigate disease manifestations from SARS-CoV-2 infection. A study among 252 patients with a COVID-19 related hospitalization reported lower risk of ICU admission (OR=0.1) and death (HR=0.3) among patients with eCoV antibodies than among patients without them.<\/li>\n<\/ul>\n<p>Sagar et al. (Sept 30, 2020). Recent Endemic Coronavirus Infection Is Associated with Less Severe COVID-19. The Journal of Clinical Investigation. <a href=\"https:\/\/doi.org\/10.1172\/JCI143380\">https:\/\/doi.org\/10.1172\/JCI143380<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pre-existing immune responses against endemic human coronaviruses (eCoVs), which are etiologic agents for the &#8220;common cold\u201d that share extensive sequence homology with SARS-CoV-2, may mitigate disease manifestations from SARS-CoV-2 infection. A study among 252 patients with a COVID-19 related hospitalization reported lower risk of ICU admission (OR=0.1) and death (HR=0.3) among patients with eCoV antibodies&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/01\/recent-endemic-coronavirus-infection-is-associated-with-less-severe-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[20],"class_list":["post-1280","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1280"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1280\/revisions"}],"predecessor-version":[{"id":1281,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1280\/revisions\/1281"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1280"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}