{"id":1304,"date":"2020-10-02T09:16:42","date_gmt":"2020-10-02T16:16:42","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1304"},"modified":"2020-10-05T09:17:39","modified_gmt":"2020-10-05T16:17:39","slug":"effectiveness-of-tests-to-detect-the-presence-of-sars-cov-2-virus-and-antibodies-to-sars-cov-2-to-inform-covid-19-diagnosis-a-rapid-systematic-review","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/02\/effectiveness-of-tests-to-detect-the-presence-of-sars-cov-2-virus-and-antibodies-to-sars-cov-2-to-inform-covid-19-diagnosis-a-rapid-systematic-review\/","title":{"rendered":"Effectiveness of Tests to Detect the Presence of SARS-CoV-2 Virus, and Antibodies to SARS-CoV-2, to Inform COVID-19 Diagnosis: A Rapid Systematic Review"},"content":{"rendered":"<ul>\n<li>A rapid systematic review of both SARS-CoV-2 virus and antibody testing found a sensitivity of 87.8% for an initial RT-PCR test, while sensitivity of antibody tests ranged from 18.4% to 96.1% and specificity ranged from 88.9% to 100%. The authors note that estimates of diagnostic accuracy should be interpreted cautiously due to the lack of a clear reference standard to diagnose or rule out SARS-CoV-2 infection. Additionally, the authors found high or unclear risks of bias in the majority of studies, due to unclear methods of patient selection and testing or use of a reference standard that may not definitively diagnose COVID\u221219.<\/li>\n<\/ul>\n<p>Jarrom et al. (Oct 1, 2020). Effectiveness of Tests to Detect the Presence of SARS-CoV-2 Virus, and Antibodies to SARS-CoV-2, to Inform COVID-19 Diagnosis: A Rapid Systematic Review. BMJ Evidence-Based Medicine. <a href=\"https:\/\/doi.org\/10.1136\/bmjebm-2020-111511\">https:\/\/doi.org\/10.1136\/bmjebm-2020-111511<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A rapid systematic review of both SARS-CoV-2 virus and antibody testing found a sensitivity of 87.8% for an initial RT-PCR test, while sensitivity of antibody tests ranged from 18.4% to 96.1% and specificity ranged from 88.9% to 100%. The authors note that estimates of diagnostic accuracy should be interpreted cautiously due to the lack of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/02\/effectiveness-of-tests-to-detect-the-presence-of-sars-cov-2-virus-and-antibodies-to-sars-cov-2-to-inform-covid-19-diagnosis-a-rapid-systematic-review\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[27],"topic":[19],"class_list":["post-1304","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1304","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1304"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1304\/revisions"}],"predecessor-version":[{"id":1305,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1304\/revisions\/1305"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1304"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1304"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1304"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1304"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}