{"id":1342,"date":"2020-10-05T09:43:30","date_gmt":"2020-10-05T16:43:30","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1342"},"modified":"2020-10-06T09:44:18","modified_gmt":"2020-10-06T16:44:18","slug":"association-of-corticosteroids-use-and-outcomes-in-covid-19-patients-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/05\/association-of-corticosteroids-use-and-outcomes-in-covid-19-patients-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Association of Corticosteroids Use and Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li>A systematic review with 1 randomized trial and 19 cohort studies (16,977 hospitalized COVID-19 patients) reported that corticosteroid therapy was not associated with a reduction in short-term mortality (RR=0.9, 95%CI 0.7-1.2) but possibly with a delay in viral clearance (RR=1.5, 95%CI 1.1-1.9). The authors call for caution in interpretation due to discordant results observed between the RCT and observational studies, as well as the heterogeneity observed across observational studies.<\/li>\n<\/ul>\n<p>Tlayjeh et al. (Sept 29, 2020). Association of Corticosteroids Use and Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis. Journal of Infection and Public Health. <a href=\"https:\/\/doi.org\/10.1016\/j.jiph.2020.09.008\">https:\/\/doi.org\/10.1016\/j.jiph.2020.09.008<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic review with 1 randomized trial and 19 cohort studies (16,977 hospitalized COVID-19 patients) reported that corticosteroid therapy was not associated with a reduction in short-term mortality (RR=0.9, 95%CI 0.7-1.2) but possibly with a delay in viral clearance (RR=1.5, 95%CI 1.1-1.9). The authors call for caution in interpretation due to discordant results observed between&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/05\/association-of-corticosteroids-use-and-outcomes-in-covid-19-patients-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-1342","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1342"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1342\/revisions"}],"predecessor-version":[{"id":1343,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1342\/revisions\/1343"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1342"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}