{"id":1425,"date":"2020-10-08T09:45:01","date_gmt":"2020-10-08T16:45:01","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1425"},"modified":"2020-10-09T09:52:04","modified_gmt":"2020-10-09T16:52:04","slug":"analysis-of-genomic-characteristics-and-transmission-routes-of-patients-with-confirmed-sars-cov-2-in-southern-california-during-the-early-stage-of-the-us-covid-19-pandemic","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/08\/analysis-of-genomic-characteristics-and-transmission-routes-of-patients-with-confirmed-sars-cov-2-in-southern-california-during-the-early-stage-of-the-us-covid-19-pandemic\/","title":{"rendered":"Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic"},"content":{"rendered":"<ul>\n<li>In a case series of 192 patients from Los Angeles, a genomic analysis found that 82% of SARS-CoV-2 isolates were most similar to isolates from Europe, while 15% were most similar to isolates from Asia. Genetic characterization of isolates identified community transmission in 13 patients, including 10 related to skilled nursing facilities, while person-to-person transmission was detected in a cluster of 5 patients. These findings highlight the utility of genomic analyses to detect transmission chains and determine the origin of viral introductions.<\/li>\n<\/ul>\n<p>Zhang et al. (Oct 7, 2020). Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic. JAMA Network Open. <a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.24191\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.24191<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a case series of 192 patients from Los Angeles, a genomic analysis found that 82% of SARS-CoV-2 isolates were most similar to isolates from Europe, while 15% were most similar to isolates from Asia. Genetic characterization of isolates identified community transmission in 13 patients, including 10 related to skilled nursing facilities, while person-to-person transmission&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/08\/analysis-of-genomic-characteristics-and-transmission-routes-of-patients-with-confirmed-sars-cov-2-in-southern-california-during-the-early-stage-of-the-us-covid-19-pandemic\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[80,38],"topic":[24],"class_list":["post-1425","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-genomics","tag-transmission","topic-geographic-spread"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1425"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1425\/revisions"}],"predecessor-version":[{"id":1426,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1425\/revisions\/1426"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1425"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}