{"id":1429,"date":"2020-10-08T10:03:08","date_gmt":"2020-10-08T17:03:08","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1429"},"modified":"2020-10-09T10:04:46","modified_gmt":"2020-10-09T17:04:46","slug":"extremely-potent-human-monoclonal-antibodies-from-convalescent-covid-19-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/08\/extremely-potent-human-monoclonal-antibodies-from-convalescent-covid-19-patients\/","title":{"rendered":"Extremely Potent Human Monoclonal Antibodies from Convalescent Covid-19 Patients"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer reviewed] Single cell sorting of 4277 SARS-CoV-2 spike protein specific memory B cells from 14 COVID-19 survivors identified 220 neutralizing antibodies that expressed as IgG. Among these, 3 monoclonal antibodies were potent enough to neutralize the wild type and DG14G mutant viruses in vitro at a concentration of &lt;10 ng\/mL, indicating they may be good candidates for further development as therapeutic tools.<\/li>\n<\/ul>\n<p>Andreano et al. (Oct 7, 2020). Extremely Potent Human Monoclonal Antibodies from Convalescent Covid-19 Patients. Pre-print downloaded Oct 8 from <a href=\"https:\/\/doi.org\/10.1101\/2020.10.07.328302\">https:\/\/doi.org\/10.1101\/2020.10.07.328302<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed] Single cell sorting of 4277 SARS-CoV-2 spike protein specific memory B cells from 14 COVID-19 survivors identified 220 neutralizing antibodies that expressed as IgG. Among these, 3 monoclonal antibodies were potent enough to neutralize the wild type and DG14G mutant viruses in vitro at a concentration of &lt;10 ng\/mL, indicating they&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/08\/extremely-potent-human-monoclonal-antibodies-from-convalescent-covid-19-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[27],"topic":[19],"class_list":["post-1429","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1429"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1429\/revisions"}],"predecessor-version":[{"id":1430,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1429\/revisions\/1430"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1429"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}