{"id":1461,"date":"2020-10-09T09:19:24","date_gmt":"2020-10-09T16:19:24","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1461"},"modified":"2020-10-12T09:20:30","modified_gmt":"2020-10-12T16:20:30","slug":"preemptive-interleukin-6-blockade-in-patients-with-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/09\/preemptive-interleukin-6-blockade-in-patients-with-covid-19\/","title":{"rendered":"Preemptive Interleukin-6 Blockade in Patients with COVID-19"},"content":{"rendered":"<ul>\n<li>Preemptive therapy with tocilizumab to prevent the consequences of cytokine storm was associated with early favorable outcomes in 77% of patients hospitalized with COVID-19 and death occurred in 6% of treated patients in a study of 64 patients in Spain. estimated mortality of 10 to 20% in comparably ill patients. <em>[EDITORIAL NOTE: The lack of a control group and the relatively small sample size limits the interpretability of these findings.]<\/em><\/li>\n<\/ul>\n<p>Guill\u00e9n et al. (Dec 8, 2020). Preemptive Interleukin-6 Blockade in Patients with COVID-19. Scientific Reports. <a href=\"https:\/\/doi.org\/10.1038\/s41598-020-74001-3\">https:\/\/doi.org\/10.1038\/s41598-020-74001-3<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Preemptive therapy with tocilizumab to prevent the consequences of cytokine storm was associated with early favorable outcomes in 77% of patients hospitalized with COVID-19 and death occurred in 6% of treated patients in a study of 64 patients in Spain. estimated mortality of 10 to 20% in comparably ill patients. [EDITORIAL NOTE: The lack of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/09\/preemptive-interleukin-6-blockade-in-patients-with-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-1461","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1461"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1461\/revisions"}],"predecessor-version":[{"id":1462,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1461\/revisions\/1462"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1461"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}