{"id":1478,"date":"2020-10-09T09:48:10","date_gmt":"2020-10-09T16:48:10","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1478"},"modified":"2020-10-12T09:48:48","modified_gmt":"2020-10-12T16:48:48","slug":"neuropathology-of-patients-with-covid-19-in-germany-a-post-mortem-case-series","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/09\/neuropathology-of-patients-with-covid-19-in-germany-a-post-mortem-case-series\/","title":{"rendered":"Neuropathology of Patients with COVID-19 in Germany: A Post-Mortem Case Series"},"content":{"rendered":"<ul>\n<li>A study of brain tissue from patients who died from COVID-19 indicated that 79% had pronounced neuroinflammatory changes in the brainstem and cerebellum, though in general, neuropathological changes seemed to be mild in most patients. SARS-CoV-2 was detected in 53% of the patients\u2019 brains, and the study found no evidence for central nervous system damage directly caused by SARS-CoV-2. The authors highlight the need for future studies to validate these findings, as no age- or sex-matched controls were included.<\/li>\n<\/ul>\n<p>Matschke et al. (Oct 2020). Neuropathology of Patients with COVID-19 in Germany: A Post-Mortem Case Series. The Lancet Neurology. <a href=\"https:\/\/doi.org\/10.1016\/S1474-4422(20)30308-2\">https:\/\/doi.org\/10.1016\/S1474-4422(20)30308-2<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study of brain tissue from patients who died from COVID-19 indicated that 79% had pronounced neuroinflammatory changes in the brainstem and cerebellum, though in general, neuropathological changes seemed to be mild in most patients. SARS-CoV-2 was detected in 53% of the patients\u2019 brains, and the study found no evidence for central nervous system damage&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/09\/neuropathology-of-patients-with-covid-19-in-germany-a-post-mortem-case-series\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-1478","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1478"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1478\/revisions"}],"predecessor-version":[{"id":1479,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1478\/revisions\/1479"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1478"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}