{"id":1491,"date":"2020-10-12T14:22:03","date_gmt":"2020-10-12T21:22:03","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1491"},"modified":"2020-10-13T14:44:42","modified_gmt":"2020-10-13T21:44:42","slug":"diagnostic-accuracy-of-fda-authorized-serology-tests-to-detect-sars-cov-2-antibodies-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/12\/diagnostic-accuracy-of-fda-authorized-serology-tests-to-detect-sars-cov-2-antibodies-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Diagnostic Accuracy of FDA Authorized Serology Tests to Detect SARS-CoV-2 Antibodies A Systematic Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer reviewed]A systematic review and meta-analysis of the diagnostic accuracy of seven different FDA-authorized tests for SARS-CoV-2 antibodies found that the pooled sensitivity was 87% and the pooled specificity was nearly 100%. Sensitivity increased with increased time between symptom onset and sample collection: at \u2264 7 days, sensitivity was 44%, for 8-14 days, sensitivity was 84%, and for blood draws \u2265 15 days after the onset of symptoms, sensitivity was 96%. The study found considerable heterogeneity between the tests and concluded that FDA authorized serology tests show high diagnostic accuracy for SARS-CoV-2 infection if performed under similar conditions.<\/li>\n<\/ul>\n<p>Pandey et al. (Oct 11, 2020). Diagnostic Accuracy of FDA Authorized Serology Tests to Detect SARS-CoV-2 Antibodies A Systematic Review and Meta-Analysis. Pre-print downloaded Oct 12 \u00a0<a href=\"https:\/\/doi.org\/10.1101\/2020.10.07.20208553\">https:\/\/doi.org\/10.1101\/2020.10.07.20208553<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed]A systematic review and meta-analysis of the diagnostic accuracy of seven different FDA-authorized tests for SARS-CoV-2 antibodies found that the pooled sensitivity was 87% and the pooled specificity was nearly 100%. Sensitivity increased with increased time between symptom onset and sample collection: at \u2264 7 days, sensitivity was 44%, for 8-14 days,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/12\/diagnostic-accuracy-of-fda-authorized-serology-tests-to-detect-sars-cov-2-antibodies-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[25,75,76,27],"topic":[19],"class_list":["post-1491","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-candidate","tag-report","tag-summarize","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1491","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1491"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1491\/revisions"}],"predecessor-version":[{"id":1492,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1491\/revisions\/1492"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1491"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1491"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1491"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1491"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}