{"id":1555,"date":"2020-10-14T13:15:31","date_gmt":"2020-10-14T20:15:31","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1555"},"modified":"2020-10-15T13:16:47","modified_gmt":"2020-10-15T20:16:47","slug":"evaluation-of-saliva-sampling-procedures-for-sars-cov-2-diagnostics-reveals-differential-sensitivity-and-association-with-viral-load","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/14\/evaluation-of-saliva-sampling-procedures-for-sars-cov-2-diagnostics-reveals-differential-sensitivity-and-association-with-viral-load\/","title":{"rendered":"Evaluation of Saliva Sampling Procedures for SARS-CoV-2 Diagnostics Reveals Differential Sensitivity and Association with Viral Load"},"content":{"rendered":"<ul>\n<li><i>[Preprint, not peer-reviewed] <\/i>Saliva collection devices showed poor sensitivities for detecting SARS-CoV-2 RNA in Belgian outpatients. Saliva samples collected either by spitting into a commercial preservative (Norgen Biotek) or swabbing (DNA Genotek) had sensitivities of 31% and 22% when compared to individuals who were PCR-positive on nasopharyngeal swabs (N=107) from outpatient triage centers in Belgium. The sensitivity was improved when the cohort was restricted to samples with medium to high viral loads (97% and 77%, respectively).<span class=\"Apple-converted-space\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i>Mestdagh et al. (Oct 13, 2020). Evaluation of Saliva Sampling Procedures for SARS-CoV-2 Diagnostics Reveals Differential Sensitivity and Association with Viral Load. Pre-print downloaded Oct 14 from <\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.10.06.20207902\">https:\/\/doi.org\/10.1101\/2020.10.06.20207902<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Preprint, not peer-reviewed] Saliva collection devices showed poor sensitivities for detecting SARS-CoV-2 RNA in Belgian outpatients. Saliva samples collected either by spitting into a commercial preservative (Norgen Biotek) or swabbing (DNA Genotek) had sensitivities of 31% and 22% when compared to individuals who were PCR-positive on nasopharyngeal swabs (N=107) from outpatient triage centers in Belgium&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/14\/evaluation-of-saliva-sampling-procedures-for-sars-cov-2-diagnostics-reveals-differential-sensitivity-and-association-with-viral-load\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[25,75,76,27],"topic":[19],"class_list":["post-1555","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-candidate","tag-report","tag-summarize","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1555"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1555\/revisions"}],"predecessor-version":[{"id":1556,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1555\/revisions\/1556"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1555"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}