{"id":1729,"date":"2020-10-22T13:30:12","date_gmt":"2020-10-22T20:30:12","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1729"},"modified":"2020-10-23T13:33:40","modified_gmt":"2020-10-23T20:33:40","slug":"efficacy-of-tocilizumab-in-patients-hospitalized-with-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/22\/efficacy-of-tocilizumab-in-patients-hospitalized-with-covid-19\/","title":{"rendered":"Efficacy of Tocilizumab in Patients Hospitalized with Covid-19"},"content":{"rendered":"<ul>\n<li>A randomized, placebo-controlled trial (n=243) demonstrated that tocilizumab (TCZ) was not effective in preventing intubation or death among moderately ill and hospitalized COVID-19 patients. At 28 days, the primary outcome of intubation or death was observed in 17 patients (10.6%) in the TCZ group and 10 patients (12.5%) in the placebo group (HR = 0.83, 95% CI = 0.38-1.81). Similar percentages of patients in the two groups received remdesivir, hydroxychloroquine, or glucocorticoids. Fewer serious infections were observed in the TCZ group (8.1% vs 17.3%, p=0.03).<\/li>\n<\/ul>\n<p>Stone et al. (Oct 21, 2020). Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. New England Journal of Medicine. <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2028836\">https:\/\/doi.org\/10.1056\/NEJMoa2028836<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A randomized, placebo-controlled trial (n=243) demonstrated that tocilizumab (TCZ) was not effective in preventing intubation or death among moderately ill and hospitalized COVID-19 patients. At 28 days, the primary outcome of intubation or death was observed in 17 patients (10.6%) in the TCZ group and 10 patients (12.5%) in the placebo group (HR = 0.83,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/22\/efficacy-of-tocilizumab-in-patients-hospitalized-with-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-1729","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1729","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1729"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1729\/revisions"}],"predecessor-version":[{"id":1730,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1729\/revisions\/1730"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1729"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1729"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1729"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1729"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}