{"id":1759,"date":"2020-10-23T09:51:05","date_gmt":"2020-10-23T16:51:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1759"},"modified":"2020-10-26T09:51:52","modified_gmt":"2020-10-26T16:51:52","slug":"early-use-of-nitazoxanide-in-mild-covid-19-disease-randomized-placebo-controlled-trial","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/23\/early-use-of-nitazoxanide-in-mild-covid-19-disease-randomized-placebo-controlled-trial\/","title":{"rendered":"Early Use of Nitazoxanide in Mild Covid-19 Disease Randomized Placebo-Controlled Trial"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer-reviewed] A multicenter, randomized, placebo-controlled trial of the antiparasitic drug nitazoxanide indicated that for patients with mild COVID-19, at 1-week follow-up, 78% of patients (n=194) who had received nitazoxanide and 57% who had received placebo (n=198) reported complete resolution of symptoms (p=0.048). Swabs collected were negative for SARS-CoV-2 in 30% of patients in the nitazoxanide group versus 18% in the placebo group (p=0.009), and viral load was significantly reduced after nitazoxanide compared to placebo (p=0.006). No deaths or life-threatening adverse events occurred in the nitazoxanide group.<\/li>\n<\/ul>\n<p>Rocco et al. (Oct 23, 2020). Early Use of Nitazoxanide in Mild Covid-19 Disease Randomized Placebo-Controlled Trial. Pre-print downloaded Oct 23 from <a href=\"https:\/\/doi.org\/10.1101\/2020.10.21.20217208\">https:\/\/doi.org\/10.1101\/2020.10.21.20217208<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A multicenter, randomized, placebo-controlled trial of the antiparasitic drug nitazoxanide indicated that for patients with mild COVID-19, at 1-week follow-up, 78% of patients (n=194) who had received nitazoxanide and 57% who had received placebo (n=198) reported complete resolution of symptoms (p=0.048). Swabs collected were negative for SARS-CoV-2 in 30% of patients in&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/23\/early-use-of-nitazoxanide-in-mild-covid-19-disease-randomized-placebo-controlled-trial\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-1759","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1759","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1759"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1759\/revisions"}],"predecessor-version":[{"id":1760,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1759\/revisions\/1760"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1759"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1759"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1759"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}