{"id":1788,"date":"2020-10-26T12:13:42","date_gmt":"2020-10-26T19:13:42","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1788"},"modified":"2020-10-27T12:15:12","modified_gmt":"2020-10-27T19:15:12","slug":"efficacy-of-hydroxychloroquine-for-post-exposure-prophylaxis-to-prevent-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-a-blinded-randomized-controlled-trial","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/26\/efficacy-of-hydroxychloroquine-for-post-exposure-prophylaxis-to-prevent-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-a-blinded-randomized-controlled-trial\/","title":{"rendered":"Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a blinded, randomized, controlled trial"},"content":{"rendered":"<p><i>[conference abstract, not peer-reviewed]<\/i> Taking a two-week course of hydroxychloroquine did not prevent SARS-CoV-2 infection among household members of people with SARS-CoV-2 in a national, household-randomized trial in the US. Among participants who were SARS-CoV-2 negative at enrollment, there were 46 new infections among participants randomized to hydroxychloroquine (n=381) and 43 in the control participants (n=400)(aHR=0.99, 95% CI 0.64-1.52). There was no difference between groups in symptomatic COVID-19 or adverse event frequency.<\/p>\n<p><i>Barnabas et al. (Oct 24, 2020). Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a blinded, randomized, controlled trial.<\/i> <a href=\"https:\/\/www.eventscribe.net\/2020\/IDWeek\/fsPopup.asp?Mode=presInfo&amp;PresentationID=798021\">https:\/\/www.eventscribe.net\/2020\/IDWeek\/fsPopup.asp?Mode=presInfo&amp;PresentationID=798021<\/a><i><span class=\"Apple-converted-space\">\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[conference abstract, not peer-reviewed] Taking a two-week course of hydroxychloroquine did not prevent SARS-CoV-2 infection among household members of people with SARS-CoV-2 in a national, household-randomized trial in the US. Among participants who were SARS-CoV-2 negative at enrollment, there were 46 new infections among participants randomized to hydroxychloroquine (n=381) and 43 in the control participants&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/26\/efficacy-of-hydroxychloroquine-for-post-exposure-prophylaxis-to-prevent-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-a-blinded-randomized-controlled-trial\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-1788","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1788"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1788\/revisions"}],"predecessor-version":[{"id":1789,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1788\/revisions\/1789"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1788"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}