{"id":1796,"date":"2020-10-26T12:23:51","date_gmt":"2020-10-26T19:23:51","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1796"},"modified":"2020-10-27T12:25:17","modified_gmt":"2020-10-27T19:25:17","slug":"outcomes-of-covid-19-related-hospitalization-among-people-with-hiv-in-the-isaric-who-clinical-characterization-protocol-uk-a-prospective-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/26\/outcomes-of-covid-19-related-hospitalization-among-people-with-hiv-in-the-isaric-who-clinical-characterization-protocol-uk-a-prospective-observational-study\/","title":{"rendered":"Outcomes of COVID-19 Related Hospitalization among People with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): A Prospective Observational Study"},"content":{"rendered":"<p>HIV-positive status was associated with an increased risk of day-28 mortality among patients hospitalized for COVID-19 in a study across more than 200 centers in the UK. Individuals presenting to the clinics who were HIV-positive were younger (median 56 versus 74 years) and had fewer comorbidities, more systemic symptoms and higher lymphocyte counts and C-reactive protein levels. Nearly 92% of HIV-positive participants were taking antiretroviral therapy. While the overall cumulative day-28 mortality was similar for HIV-positive and HIV-negative groups (27% vs. 32%), among individuals younger than 60, HIV-positive status was associated with greater mortality (21% vs. 10%), and mortality was higher among people with HIV after adjusting for age (aHR = 1.47).<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p><i>Geretti et al. (Oct 23, 2020). Outcomes of COVID-19 Related Hospitalization among People with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): A Prospective Observational Study. Clinical Infectious Diseases.<\/i> <a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1605\">https:\/\/doi.org\/10.1093\/cid\/ciaa1605<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>HIV-positive status was associated with an increased risk of day-28 mortality among patients hospitalized for COVID-19 in a study across more than 200 centers in the UK. Individuals presenting to the clinics who were HIV-positive were younger (median 56 versus 74 years) and had fewer comorbidities, more systemic symptoms and higher lymphocyte counts and C-reactive&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/26\/outcomes-of-covid-19-related-hospitalization-among-people-with-hiv-in-the-isaric-who-clinical-characterization-protocol-uk-a-prospective-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[46],"topic":[20],"class_list":["post-1796","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-risk-factors","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1796","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1796"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1796\/revisions"}],"predecessor-version":[{"id":1797,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1796\/revisions\/1797"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1796"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}