{"id":1819,"date":"2020-10-27T12:18:15","date_gmt":"2020-10-27T19:18:15","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1819"},"modified":"2020-10-28T12:19:52","modified_gmt":"2020-10-28T19:19:52","slug":"longitudinal-observation-and-decline-of-neutralizing-antibody-responses-in-the-three-months-following-sars-cov-2-infection-in-humans","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/27\/longitudinal-observation-and-decline-of-neutralizing-antibody-responses-in-the-three-months-following-sars-cov-2-infection-in-humans\/","title":{"rendered":"Longitudinal Observation and Decline of Neutralizing Antibody Responses in the Three Months Following SARS-CoV-2 Infection in Humans"},"content":{"rendered":"<p>A longitudinal study that followed 65 SARS-CoV-2 infected individuals up to 94 days post onset of symptoms found that the neutralizing antibody (nAb) response to SARS-CoV-2 is typical of an acute viral infection, with an initial peak whose magnitude is dependent upon disease severity, followed by declining titers. Some infected individuals with a high peak infective dose (ID<sub>50<\/sub> &gt; 10,000) were found to maintain nAb titers &gt;1,000 at &gt;60 days post symptom onset, while some with lower peak ID<sub>50<\/sub> had nAbs titers similar to baseline.<\/p>\n<p><i>Seow et al. (Oct 26, 2020). Longitudinal Observation and Decline of Neutralizing Antibody Responses in the Three Months Following SARS-CoV-2 Infection in Humans. Nature Microbiology. <\/i><a href=\"https:\/\/doi.org\/10.1038\/s41564-020-00813-8\">https:\/\/doi.org\/10.1038\/s41564-020-00813-8<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A longitudinal study that followed 65 SARS-CoV-2 infected individuals up to 94 days post onset of symptoms found that the neutralizing antibody (nAb) response to SARS-CoV-2 is typical of an acute viral infection, with an initial peak whose magnitude is dependent upon disease severity, followed by declining titers. Some infected individuals with a high peak&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/27\/longitudinal-observation-and-decline-of-neutralizing-antibody-responses-in-the-three-months-following-sars-cov-2-infection-in-humans\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,76],"topic":[31],"class_list":["post-1819","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-summarize","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1819","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1819"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1819\/revisions"}],"predecessor-version":[{"id":1820,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1819\/revisions\/1820"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1819"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1819"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1819"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1819"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}