{"id":1872,"date":"2020-10-29T11:15:36","date_gmt":"2020-10-29T18:15:36","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1872"},"modified":"2020-10-30T11:51:32","modified_gmt":"2020-10-30T18:51:32","slug":"sars-cov-2-neutralizing-antibody-ly-cov555-in-outpatients-with-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/29\/sars-cov-2-neutralizing-antibody-ly-cov555-in-outpatients-with-covid-19\/","title":{"rendered":"SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19"},"content":{"rendered":"<ul>\n<li>A phase 2 randomized placebo-controlled trial (n=452) interim analysis found that patients who received a 2800mg dose of monoclonal antibody LY-CoV555 could reduce SARS-CoV-2 log viral load by 3.4-fold after 11 days compared to patients receiving placebo, corresponding to a 0.53 log viral load reduction (95% CI: -0.98 to -0.08). Other patients receiving a 700mg dose (n=101) or a 7000mg dose (n=101) experienced smaller differences.<\/li>\n<\/ul>\n<p>Chen et al. (Oct 28, 2020). SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19. New England Journal of Medicine. <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2029849\">https:\/\/doi.org\/10.1056\/NEJMoa2029849<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A phase 2 randomized placebo-controlled trial (n=452) interim analysis found that patients who received a 2800mg dose of monoclonal antibody LY-CoV555 could reduce SARS-CoV-2 log viral load by 3.4-fold after 11 days compared to patients receiving placebo, corresponding to a 0.53 log viral load reduction (95% CI: -0.98 to -0.08). Other patients receiving a 700mg&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/10\/29\/sars-cov-2-neutralizing-antibody-ly-cov555-in-outpatients-with-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,28],"topic":[31],"class_list":["post-1872","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-treatment","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1872","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1872"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1872\/revisions"}],"predecessor-version":[{"id":1873,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1872\/revisions\/1873"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1872"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}