{"id":1961,"date":"2020-11-03T13:39:17","date_gmt":"2020-11-03T21:39:17","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=1961"},"modified":"2020-11-04T13:40:54","modified_gmt":"2020-11-04T21:40:54","slug":"robust-sars-cov-2-specific-t-cell-immunity-is-maintained-at-6-months-following-primary-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/03\/robust-sars-cov-2-specific-t-cell-immunity-is-maintained-at-6-months-following-primary-infection\/","title":{"rendered":"Robust SARS-CoV-2-Specific T-Cell Immunity Is Maintained at 6 Months Following Primary Infection"},"content":{"rendered":"<p><i>[Pre-print, not peer-reviewed]<\/i> Blood samples from 100 convalescent donors 6 months after their initial SARS-CoV-2 infection found that T-cell responses against SARS-CoV-2 were present in all donors. The median response was 50% higher among donors with an initial symptomatic infection. T-cell responses to both spike and nucleoprotein\/membrane proteins strongly correlated with peak antibody levels against each respective protein. A reduced rate of antibody level decline was strongly correlated with the magnitude of T-cell response, though this relationship was only observed for antibodies specific to the nucleoprotein.<\/p>\n<p><i>Zuo et al. (Nov 2, 2020). Robust SARS-CoV-2-Specific T-Cell Immunity Is Maintained at 6 Months Following Primary Infection. Pre-print downloaded Nov 3 from <\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.11.01.362319\">https:\/\/doi.org\/10.1101\/2020.11.01.362319<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Blood samples from 100 convalescent donors 6 months after their initial SARS-CoV-2 infection found that T-cell responses against SARS-CoV-2 were present in all donors. The median response was 50% higher among donors with an initial symptomatic infection. T-cell responses to both spike and nucleoprotein\/membrane proteins strongly correlated with peak antibody levels against&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/03\/robust-sars-cov-2-specific-t-cell-immunity-is-maintained-at-6-months-following-primary-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,32],"topic":[31],"class_list":["post-1961","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=1961"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1961\/revisions"}],"predecessor-version":[{"id":1962,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/1961\/revisions\/1962"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=1961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=1961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=1961"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=1961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}