{"id":2040,"date":"2020-11-06T09:59:46","date_gmt":"2020-11-06T17:59:46","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2040"},"modified":"2020-11-09T10:01:32","modified_gmt":"2020-11-09T18:01:32","slug":"viral-rna-level-serum-antibody-responses-and-transmission-risk-in-recovered-covid-19-patients-with-recurrent-positive-sars-cov-2-rna-test-results-a-population-based-observational-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/06\/viral-rna-level-serum-antibody-responses-and-transmission-risk-in-recovered-covid-19-patients-with-recurrent-positive-sars-cov-2-rna-test-results-a-population-based-observational-cohort-study\/","title":{"rendered":"Viral RNA Level, Serum Antibody Responses, and Transmission Risk in Recovered COVID-19 Patients with Recurrent Positive SARS-CoV-2 RNA Test Results: A Population-Based Observational Cohort Study"},"content":{"rendered":"<ul>\n<li>Intermittent excretion of low levels of SARS-CoV-2 RNA after hospital discharge was not associated with either secondary transmission or worsening clinical disease. A population-based observational study of patients in China who had clinically recovered from SARS-CoV-2 and satisfied criteria for discharge including two negative PCR tests were then re-tested as outpatients. 479 patients were found to be SARS-CoV-2 positive with a median time-to-positivity of five days. These patients were re-admitted and this population exhibited mild (28%) or no (72%) symptoms with significantly lower levels of viral RNA than the corresponding values at disease onset. 96 close contacts and 1,200 candidate contacts of 23 recurrent-positive patients showed no clinical symptoms. The authors conclude that recurrent-positive patients pose a low transmission risk.<\/li>\n<\/ul>\n<p>Yang et al. (Jan 1, 2020). Viral RNA Level, Serum Antibody Responses, and Transmission Risk in Recovered COVID-19 Patients with Recurrent Positive SARS-CoV-2 RNA Test Results: A Population-Based Observational Cohort Study. Emerging Microbes &amp; Infections. <a href=\"https:\/\/doi.org\/10.1080\/22221751.2020.1837018\">https:\/\/doi.org\/10.1080\/22221751.2020.1837018<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Intermittent excretion of low levels of SARS-CoV-2 RNA after hospital discharge was not associated with either secondary transmission or worsening clinical disease. A population-based observational study of patients in China who had clinically recovered from SARS-CoV-2 and satisfied criteria for discharge including two negative PCR tests were then re-tested as outpatients. 479 patients were found&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/06\/viral-rna-level-serum-antibody-responses-and-transmission-risk-in-recovered-covid-19-patients-with-recurrent-positive-sars-cov-2-rna-test-results-a-population-based-observational-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,34],"topic":[20],"class_list":["post-2040","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2040"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2040\/revisions"}],"predecessor-version":[{"id":2041,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2040\/revisions\/2041"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2040"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}