{"id":2127,"date":"2020-11-12T17:50:17","date_gmt":"2020-11-13T01:50:17","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2127"},"modified":"2020-11-13T17:51:44","modified_gmt":"2020-11-14T01:51:44","slug":"seasonal-human-coronavirus-antibodies-are-boosted-upon-sars-cov-2-infection-but-not-associated-with-protection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/12\/seasonal-human-coronavirus-antibodies-are-boosted-upon-sars-cov-2-infection-but-not-associated-with-protection\/","title":{"rendered":"Seasonal Human Coronavirus Antibodies Are Boosted upon SARS-CoV-2 Infection but Not Associated with Protection"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer reviewed] An analysis suggests that prior infection with human coronaviruses other than SARS-CoV-2 is not associated with protection from SARS-CoV-2 infection. The authors found no significant differences in the levels of pre-pandemic human coronavirus antibodies cross-reactive to SARS-CoV-2 proteins between a cohort of people eventually infected with SARS-CoV-2 (n=251) and a matched cohort who was not (n=251). This relationship held even after analyzing a smaller cohort (39 SARS-CoV-2 infected, 57 non-infected) whose pre-pandemic serum samples were collected a year before March 2020.<\/li>\n<li>Meanwhile, longitudinal analysis of a separate cohort of 27 COVID-19 patients found that SARS-CoV-2 infection boosts antibodies reactive to other human coronaviruses.<\/li>\n<\/ul>\n<p>Anderson et al. (Nov 10, 2020). Seasonal Human Coronavirus Antibodies Are Boosted upon SARS-CoV-2 Infection but Not Associated with Protection. Pre-print downloaded Nov 12 from <a href=\"https:\/\/doi.org\/10.1101\/2020.11.06.20227215\">https:\/\/doi.org\/10.1101\/2020.11.06.20227215<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed] An analysis suggests that prior infection with human coronaviruses other than SARS-CoV-2 is not associated with protection from SARS-CoV-2 infection. The authors found no significant differences in the levels of pre-pandemic human coronavirus antibodies cross-reactive to SARS-CoV-2 proteins between a cohort of people eventually infected with SARS-CoV-2 (n=251) and a matched&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/12\/seasonal-human-coronavirus-antibodies-are-boosted-upon-sars-cov-2-infection-but-not-associated-with-protection\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-2127","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2127","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2127"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2127\/revisions"}],"predecessor-version":[{"id":2128,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2127\/revisions\/2128"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2127"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2127"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2127"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}