{"id":2163,"date":"2020-11-13T11:06:36","date_gmt":"2020-11-13T19:06:36","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2163"},"modified":"2020-11-16T11:07:55","modified_gmt":"2020-11-16T19:07:55","slug":"diagnosis-and-tracking-of-past-sars-cov-2-infection-in-a-large-study-of-vo-italy-through-t-cell-receptor-sequencing","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/13\/diagnosis-and-tracking-of-past-sars-cov-2-infection-in-a-large-study-of-vo-italy-through-t-cell-receptor-sequencing\/","title":{"rendered":"Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo\u2019 Italy Through T-Cell Receptor Sequencing"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer-reviewed] The presence of T-cells reactive to SARS-CoV-2 was found to be a strong indicator of past SARS-CoV-2 infection. In a large population study (n = 2,200) in Italy that included 70 individuals with PCR-confirmed SARS-CoV-2 infection, blood samples taken 60 days after PCR diagnosis indicated that 97% of the people with PCR-confirmed infection had a positive T-cell test result. This percentage was higher than the antibody serology assay (77%). The T-cell response was associated with disease severity, with significantly higher response among people who were symptomatic or hospitalized compared to those who were asymptomatic.<\/li>\n<\/ul>\n<p>Gittelman et al. (Nov 12, 2020). Diagnosis and Tracking of Past SARS-CoV-2 Infection in a Large Study of Vo\u2019 Italy Through T-Cell Receptor Sequencing. MedRxiv. <a href=\"https:\/\/doi.org\/10.1101\/2020.11.09.20228023\">https:\/\/doi.org\/10.1101\/2020.11.09.20228023<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] The presence of T-cells reactive to SARS-CoV-2 was found to be a strong indicator of past SARS-CoV-2 infection. In a large population study (n = 2,200) in Italy that included 70 individuals with PCR-confirmed SARS-CoV-2 infection, blood samples taken 60 days after PCR diagnosis indicated that 97% of the people with PCR-confirmed&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/13\/diagnosis-and-tracking-of-past-sars-cov-2-infection-in-a-large-study-of-vo-italy-through-t-cell-receptor-sequencing\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67],"topic":[31],"class_list":["post-2163","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2163","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2163"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2163\/revisions"}],"predecessor-version":[{"id":2164,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2163\/revisions\/2164"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2163"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2163"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2163"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}