{"id":2298,"date":"2020-11-20T10:07:47","date_gmt":"2020-11-20T18:07:47","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2298"},"modified":"2020-11-23T10:20:11","modified_gmt":"2020-11-23T18:20:11","slug":"antibodies-to-sars-cov-2-are-associated-with-protection-against-reinfection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/20\/antibodies-to-sars-cov-2-are-associated-with-protection-against-reinfection\/","title":{"rendered":"Antibodies to SARS-CoV-2 are associated with protection against Reinfection"},"content":{"rendered":"<ul>\n<li>[Pre-print, not peer reviewed] A prospective longitudinal cohort study of healthcare workers shows that antibodies against the spike protein of SARS-CoV-2 (suggesting previous infection) are associated with lower risk of a PCR-positive test (IRR: 0.24, 95% CI: 0.08-0.76). The study included 11,052 seronegative individuals and 1,246 seropositive individuals. No symptomatic infections and only three asymptomatic PCR-positive results (0.21 cases per 10,000 days at risk) were seen in those with anti-spike antibodies, over 30 weeks of follow-up. By comparison, among the initially seronegative individuals there were 89 PCR-confirmed symptomatic cases (0.46 cases per 10,000 days at risk) and 76 confirmed asymptomatic cases (0.40\/10,000 days at risk). The authors conclude that these results provide evidence that antibodies produced by prior SARS-CoV-2 infection are associated with at least partial protection against reinfection for at least six months.<\/li>\n<\/ul>\n<p>Lumley et al. (Nov 18, 2020). Antibodies to SARS-CoV-2 are associated with protection against Reinfection. Pre-print downloaded Nov 19 from <a href=\"https:\/\/doi.org\/10.1101\/2020.11.18.20234369\">https:\/\/doi.org\/10.1101\/2020.11.18.20234369<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed] A prospective longitudinal cohort study of healthcare workers shows that antibodies against the spike protein of SARS-CoV-2 (suggesting previous infection) are associated with lower risk of a PCR-positive test (IRR: 0.24, 95% CI: 0.08-0.76). The study included 11,052 seronegative individuals and 1,246 seropositive individuals. No symptomatic infections and only three asymptomatic&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/20\/antibodies-to-sars-cov-2-are-associated-with-protection-against-reinfection\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67],"topic":[31],"class_list":["post-2298","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2298","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2298"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2298\/revisions"}],"predecessor-version":[{"id":2299,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2298\/revisions\/2299"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2298"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2298"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2298"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2298"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}