{"id":2367,"date":"2020-11-24T12:35:43","date_gmt":"2020-11-24T20:35:43","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2367"},"modified":"2020-11-25T12:55:56","modified_gmt":"2020-11-25T20:55:56","slug":"a-randomized-trial-of-convalescent-plasma-in-covid-19-severe-pneumonia","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/24\/a-randomized-trial-of-convalescent-plasma-in-covid-19-severe-pneumonia\/","title":{"rendered":"A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia"},"content":{"rendered":"<p>A randomized placebo-controlled trial of convalescent plasma (CP) infusion for patients with severe COVID-19 (n=228) found no significant difference between the treatment and placebo groups in the improvement in clinical status measured at 30 days using an ordinal scale (OR=0.83, 95%CI 0.52 \u2013 1.35). Overall mortality was 11% in the CP group and 11.4% in the placebo group. Adverse events were similar in the two groups. The infused CP had a median titer of 1:3200 of total SARS-CoV-2 antibodies.<\/p>\n<p><i>Simonovich et al. (Nov 24, 2020). A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia. New England Journal of Medicine.<\/i> <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2031304\">https:\/\/doi.org\/10.1056\/NEJMoa2031304<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A randomized placebo-controlled trial of convalescent plasma (CP) infusion for patients with severe COVID-19 (n=228) found no significant difference between the treatment and placebo groups in the improvement in clinical status measured at 30 days using an ordinal scale (OR=0.83, 95%CI 0.52 \u2013 1.35). Overall mortality was 11% in the CP group and 11.4% in&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/24\/a-randomized-trial-of-convalescent-plasma-in-covid-19-severe-pneumonia\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-2367","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2367"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2367\/revisions"}],"predecessor-version":[{"id":2368,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2367\/revisions\/2368"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2367"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}