{"id":2443,"date":"2020-11-30T12:57:00","date_gmt":"2020-11-30T20:57:00","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2443"},"modified":"2020-12-01T12:58:52","modified_gmt":"2020-12-01T20:58:52","slug":"are-psychiatric-disorders-risk-factors-for-covid-19-susceptibility-and-severity-a-two-sample-bidirectional-univariable-and-multivariable-mendelian-randomization-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/30\/are-psychiatric-disorders-risk-factors-for-covid-19-susceptibility-and-severity-a-two-sample-bidirectional-univariable-and-multivariable-mendelian-randomization-study\/","title":{"rendered":"Are Psychiatric Disorders Risk Factors for COVID-19 Susceptibility and Severity: A Two-Sample Bidirectional Univariable and Multivariable Mendelian Randomization Study"},"content":{"rendered":"<p><i>[Pre-print, not peer-reviewed]<\/i> An analysis of potential bidirectional relationships between neuropsychiatric disorders and COVID-19 showed that genetic liability to bipolar disorder slightly increased COVID-19 susceptibility and severity, and there was no consistent evidence of COVID-19 influencing risk of developing psychiatric disorders. A combination of bipolar disorder and schizophrenia was associated with greater risk of contracting SARS-CoV-2 in a univariable Mendelian randomization analysis.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p><i>Luykx et al. (Nov 30, 2020). Are Psychiatric Disorders Risk Factors for COVID-19 Susceptibility and Severity: A Two-Sample Bidirectional Univariable and Multivariable Mendelian Randomization Study. <\/i><i>Pre-print downloaded Nov. 30 from<\/i><i> <\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.11.29.20240481\">https:\/\/doi.org\/10.1101\/2020.11.29.20240481<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] An analysis of potential bidirectional relationships between neuropsychiatric disorders and COVID-19 showed that genetic liability to bipolar disorder slightly increased COVID-19 susceptibility and severity, and there was no consistent evidence of COVID-19 influencing risk of developing psychiatric disorders. A combination of bipolar disorder and schizophrenia was associated with greater risk of contracting&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/11\/30\/are-psychiatric-disorders-risk-factors-for-covid-19-susceptibility-and-severity-a-two-sample-bidirectional-univariable-and-multivariable-mendelian-randomization-study\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[46],"topic":[20],"class_list":["post-2443","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-risk-factors","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2443"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2443\/revisions"}],"predecessor-version":[{"id":2444,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2443\/revisions\/2444"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2443"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2443"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}