{"id":2532,"date":"2020-12-03T08:13:51","date_gmt":"2020-12-03T16:13:51","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2532"},"modified":"2020-12-04T08:16:08","modified_gmt":"2020-12-04T16:16:08","slug":"predicted-cellular-immunity-population-coverage-gaps-for-sars-cov-2-subunit-vaccines-and-their-augmentation-by-compact-peptide-sets","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/03\/predicted-cellular-immunity-population-coverage-gaps-for-sars-cov-2-subunit-vaccines-and-their-augmentation-by-compact-peptide-sets\/","title":{"rendered":"Predicted Cellular Immunity Population Coverage Gaps for SARS-CoV-2 Subunit Vaccines and Their Augmentation by Compact Peptide Sets"},"content":{"rendered":"<ul>\n<li>Using machine learning predictions and clinical data from convalescent COVID-19 patients, Liu et al. developed a vaccine design that would incorporate enough pathogen components to elicit an immune response across a diverse population of people. The study also indicates that current vaccine candidates, which are largely based only on the SARS-CoV-2 spike protein and receptor binding domain (RBD), may have gaps in their effectiveness to elicit an immune response that depend on a person&#8217;s genetic ancestry.<\/li>\n<\/ul>\n<p>Liu et al. (Nov 27, 2020). Predicted Cellular Immunity Population Coverage Gaps for SARS-CoV-2 Subunit Vaccines and Their Augmentation by Compact Peptide Sets. Cell Systems. <a href=\"https:\/\/doi.org\/10.1016\/j.cels.2020.11.010\">https:\/\/doi.org\/10.1016\/j.cels.2020.11.010<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using machine learning predictions and clinical data from convalescent COVID-19 patients, Liu et al. developed a vaccine design that would incorporate enough pathogen components to elicit an immune response across a diverse population of people. The study also indicates that current vaccine candidates, which are largely based only on the SARS-CoV-2 spike protein and receptor&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/03\/predicted-cellular-immunity-population-coverage-gaps-for-sars-cov-2-subunit-vaccines-and-their-augmentation-by-compact-peptide-sets\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[42,33],"topic":[31],"class_list":["post-2532","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-disparities","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2532","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2532"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2532\/revisions"}],"predecessor-version":[{"id":2533,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2532\/revisions\/2533"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2532"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2532"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2532"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2532"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}