{"id":2587,"date":"2020-12-07T12:10:36","date_gmt":"2020-12-07T20:10:36","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2587"},"modified":"2020-12-08T12:12:29","modified_gmt":"2020-12-08T20:12:29","slug":"sars-cov-2-rna-detected-in-blood-products-from-patients-with-covid-19-is-not-associated-with-infectious-virus","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/07\/sars-cov-2-rna-detected-in-blood-products-from-patients-with-covid-19-is-not-associated-with-infectious-virus\/","title":{"rendered":"SARS-CoV-2 RNA Detected in Blood Products from Patients with COVID-19 Is Not Associated with Infectious Virus"},"content":{"rendered":"<p>A systematic review of 28 studies intended to inform safety protocols for handling blood products from people with COVID-19 found there were low levels of detectable SARS-CoV-2 RNA in a minority of serum samples (pooled estimate 10%) collected during acute infection.<span class=\"Apple-converted-space\">\u00a0<\/span>In an associated laboratory analysis, the authors also performed RT-PCR in serum samples from a clinical cohort of people who recovered from COVID-19 (n=212 samples from 167 patients), and 12.7% had RNA detected by RT-PCR. Across all samples collected \u226528 days post-symptom onset, 0\/494 had viral RNA. PCR-positive sera inoculated into cell culture did not produce any cytopathic effect or yield an increase in detectable SARS-CoV-2 RNA.<\/p>\n<p><i>Andersson et al. (Oct 12, 2020). SARS-CoV-2 RNA Detected in Blood Products from Patients with COVID-19 Is Not Associated with Infectious Virus. Wellcome Open Research. <\/i><a href=\"https:\/\/doi.org\/10.12688\/wellcomeopenres.16002.1\">https:\/\/doi.org\/10.12688\/wellcomeopenres.16002.1<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic review of 28 studies intended to inform safety protocols for handling blood products from people with COVID-19 found there were low levels of detectable SARS-CoV-2 RNA in a minority of serum samples (pooled estimate 10%) collected during acute infection.\u00a0In an associated laboratory analysis, the authors also performed RT-PCR in serum samples from a&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/07\/sars-cov-2-rna-detected-in-blood-products-from-patients-with-covid-19-is-not-associated-with-infectious-virus\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[38],"topic":[21],"class_list":["post-2587","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-transmission","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2587"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2587\/revisions"}],"predecessor-version":[{"id":2588,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2587\/revisions\/2588"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2587"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}