{"id":2693,"date":"2020-12-11T16:08:36","date_gmt":"2020-12-12T00:08:36","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2693"},"modified":"2020-12-14T16:10:07","modified_gmt":"2020-12-15T00:10:07","slug":"sars-cov-2-sars-cov-and-mers-cov-viral-load-dynamics-duration-of-viral-shedding-and-infectiousness-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/11\/sars-cov-2-sars-cov-and-mers-cov-viral-load-dynamics-duration-of-viral-shedding-and-infectiousness-a-systematic-review-and-meta-analysis\/","title":{"rendered":"SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis"},"content":{"rendered":"<ul>\n<li>A meta-analysis of viral RNA shedding of SARS-CoV-2 (79 studies, 5,340 individuals), SARS-CoV (8 studies, 1,858 individuals), and MERS-CoV (11 studies, 799 individuals) found the mean duration of SARS-CoV-2 RNA shedding was 17 days in upper respiratory tract, 14.6 days in lower respiratory tract, 17.2 days in stool, and 16.6 days in serum samples. No study detected live SARS-CoV-2 from culture beyond day 9 of symptoms despite persistently high viral RNA loads. The viral load of SARS-CoV-2 appeared to peak in the first week after symptom onset, compared to peaks at days 10-14 for SARS-CoV and days 7-10 for MERS-CoV.<\/li>\n<\/ul>\n<p>Cevik et al. (Dec 11, 2020). SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis. The Lancet Microbe. \u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1016\/S2666-5247(20)30172-5\">https:\/\/doi.org\/10.1016\/S2666-5247(20)30172-5<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A meta-analysis of viral RNA shedding of SARS-CoV-2 (79 studies, 5,340 individuals), SARS-CoV (8 studies, 1,858 individuals), and MERS-CoV (11 studies, 799 individuals) found the mean duration of SARS-CoV-2 RNA shedding was 17 days in upper respiratory tract, 14.6 days in lower respiratory tract, 17.2 days in stool, and 16.6 days in serum samples. No&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/11\/sars-cov-2-sars-cov-and-mers-cov-viral-load-dynamics-duration-of-viral-shedding-and-infectiousness-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[38],"topic":[21],"class_list":["post-2693","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-transmission","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2693"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2693\/revisions"}],"predecessor-version":[{"id":2694,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2693\/revisions\/2694"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2693"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}