{"id":2695,"date":"2020-12-11T16:11:12","date_gmt":"2020-12-12T00:11:12","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2695"},"modified":"2020-12-14T16:14:38","modified_gmt":"2020-12-15T00:14:38","slug":"false-negative-results-of-initial-rt-pcr-assays-for-covid-19-a-systematic-review","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/11\/false-negative-results-of-initial-rt-pcr-assays-for-covid-19-a-systematic-review\/","title":{"rendered":"False-negative results of initial RT-PCR assays for COVID-19: A systematic review"},"content":{"rendered":"<ul>\n<li>A systematic review of 34 studies (12,057 patients) on detection of SARS-CoV-2 by RT-PCR assays at first use estimated a false-negative rate of 13% (95% CI 9% to 19%), though identified substantial heterogeneity between studies, which ranged in their individual estimates from 1.8% to 58%. The authors were unable to investigate most potential sources of heterogeneity due to data limitations. Only 9 studies reported the interval between symptom onset and testing.<\/li>\n<\/ul>\n<p>Arevalo-Rodriguez et al. (Dec 10, 2020). False-negative results of initial RT-PCR assays for COVID-19: A systematic review. PLOS ONE. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0242958\">https:\/\/doi.org\/10.1371\/journal.pone.0242958<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic review of 34 studies (12,057 patients) on detection of SARS-CoV-2 by RT-PCR assays at first use estimated a false-negative rate of 13% (95% CI 9% to 19%), though identified substantial heterogeneity between studies, which ranged in their individual estimates from 1.8% to 58%. The authors were unable to investigate most potential sources of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/11\/false-negative-results-of-initial-rt-pcr-assays-for-covid-19-a-systematic-review\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[27],"topic":[19],"class_list":["post-2695","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2695","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2695"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2695\/revisions"}],"predecessor-version":[{"id":2696,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2695\/revisions\/2696"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2695"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2695"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2695"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2695"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}