{"id":2970,"date":"2020-12-30T13:10:41","date_gmt":"2020-12-30T21:10:41","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=2970"},"modified":"2020-12-31T13:11:59","modified_gmt":"2020-12-31T21:11:59","slug":"immune-deficiency-is-a-risk-factor-for-severe-covid%e2%80%9019-in-people-living-with-hiv","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/30\/immune-deficiency-is-a-risk-factor-for-severe-covid%e2%80%9019-in-people-living-with-hiv\/","title":{"rendered":"Immune Deficiency Is a Risk Factor for Severe COVID\u201019 in People Living with HIV"},"content":{"rendered":"<p>Among 175 people living with HIV in the UK, US, and Spain, a current CD4 T-cell count of &lt;350 cells\/\u00b5L was independently associated with a 2.85-fold risk for developing severe COVID-19. A lower nadir CD4 T-cell count of &lt;200 cells\/\u00b5L was associated with mortality. No significant differences in risk of severe or critical COVID-19 were detected by gender, ethnicity, obesity, detectable HIV RNA, prior AIDS\u2010defining illness, tenofovir, or protease inhibitor use in the current antiretroviral treatment.<\/p>\n<p><i>Hoffmann et al. (Dec 27, 2020). Immune Deficiency Is a Risk Factor for Severe COVID\u201019 in People Living with HIV. HIV Medicine. <\/i><a href=\"https:\/\/doi.org\/10.1111\/hiv.13037\">https:\/\/doi.org\/10.1111\/hiv.13037<\/a><i><span class=\"Apple-converted-space\">\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Among 175 people living with HIV in the UK, US, and Spain, a current CD4 T-cell count of &lt;350 cells\/\u00b5L was independently associated with a 2.85-fold risk for developing severe COVID-19. A lower nadir CD4 T-cell count of &lt;200 cells\/\u00b5L was associated with mortality. No significant differences in risk of severe or critical COVID-19 were&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/12\/30\/immune-deficiency-is-a-risk-factor-for-severe-covid%e2%80%9019-in-people-living-with-hiv\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[46],"topic":[20],"class_list":["post-2970","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-risk-factors","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2970","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=2970"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2970\/revisions"}],"predecessor-version":[{"id":2971,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/2970\/revisions\/2971"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=2970"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=2970"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=2970"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=2970"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}