{"id":3155,"date":"2021-01-11T20:16:43","date_gmt":"2021-01-12T04:16:43","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3155"},"modified":"2021-01-11T20:16:43","modified_gmt":"2021-01-12T04:16:43","slug":"prevalence-and-clinical-significance-of-persistent-viral-shedding-in-hospitalized-adult-patients-with-sars-cov-2-infection-a-prospective-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/11\/prevalence-and-clinical-significance-of-persistent-viral-shedding-in-hospitalized-adult-patients-with-sars-cov-2-infection-a-prospective-observational-study\/","title":{"rendered":"Prevalence and Clinical Significance of Persistent Viral Shedding in Hospitalized Adult Patients with SARS-CoV-2 Infection: A Prospective Observational Study"},"content":{"rendered":"<p>A prospective observational study of adults hospitalized with SARS-CoV-2 infection (n=121) detected persistent viral shedding (PVS) for at least 21 days in up to 38% of patients, which was strongly associated with immunosuppression (6.7% vs 21.7%), increased IL-6 levels (43.4% vs 67.3%), and need for mechanical ventilation (20.0% vs 41.3%). Time from onset of symptoms was also an independent factor associated with PVS in the multivariate analysis.<\/p>\n<p><i>Vena et al. (Jan 8, 2021). Prevalence and Clinical Significance of Persistent Viral Shedding in Hospitalized Adult Patients with SARS-CoV-2 Infection: A Prospective Observational Study. Infectious Diseases and Therapy. <\/i><a href=\"https:\/\/doi.org\/10.1007\/s40121-020-00381-8\">https:\/\/doi.org\/10.1007\/s40121-020-00381-8<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A prospective observational study of adults hospitalized with SARS-CoV-2 infection (n=121) detected persistent viral shedding (PVS) for at least 21 days in up to 38% of patients, which was strongly associated with immunosuppression (6.7% vs 21.7%), increased IL-6 levels (43.4% vs 67.3%), and need for mechanical ventilation (20.0% vs 41.3%). Time from onset of symptoms&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/11\/prevalence-and-clinical-significance-of-persistent-viral-shedding-in-hospitalized-adult-patients-with-sars-cov-2-infection-a-prospective-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-3155","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3155","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3155"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3155\/revisions"}],"predecessor-version":[{"id":3156,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3155\/revisions\/3156"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3155"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3155"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3155"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3155"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}