{"id":3324,"date":"2021-01-20T13:47:11","date_gmt":"2021-01-20T21:47:11","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3324"},"modified":"2021-01-21T13:48:01","modified_gmt":"2021-01-21T21:48:01","slug":"do-antibody-positive-healthcare-workers-have-lower-sars-cov-2-infection-rates-than-antibody-negative-healthcare-workers-large-multi-centre-prospective-cohort-study-the-siren-study-england-june-to-no","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/20\/do-antibody-positive-healthcare-workers-have-lower-sars-cov-2-infection-rates-than-antibody-negative-healthcare-workers-large-multi-centre-prospective-cohort-study-the-siren-study-england-june-to-no\/","title":{"rendered":"Do Antibody Positive Healthcare Workers Have Lower SARS-CoV-2 Infection Rates than Antibody Negative Healthcare Workers Large Multi-Centre Prospective Cohort Study (the SIREN Study) England June to November 2020"},"content":{"rendered":"<p>Prior history of SARS-CoV-2 infection was associated with an 83% lower risk of infection in a large, multicenter, prospective cohort study (SIREN) of healthcare workers in England, with median protective effect observed five months following primary infection. The incidence between June 18-November 9, 2020 was 3.3 reinfections per 100,000 person days in the previously-infected cohort, compared with 22.4 new PCR confirmed infections per 100,000 person days in the uninfected cohort.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p><i>Hall et al. (Jan 15, 2021). Do Antibody Positive Healthcare Workers Have Lower SARS-CoV-2 Infection Rates than Antibody Negative Healthcare Workers Large Multi-Centre Prospective Cohort Study (the SIREN Study) England June to November 2020. MedRxiv. <\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.01.13.21249642\">https:\/\/doi.org\/10.1101\/2021.01.13.21249642<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prior history of SARS-CoV-2 infection was associated with an 83% lower risk of infection in a large, multicenter, prospective cohort study (SIREN) of healthcare workers in England, with median protective effect observed five months following primary infection. The incidence between June 18-November 9, 2020 was 3.3 reinfections per 100,000 person days in the previously-infected cohort,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/20\/do-antibody-positive-healthcare-workers-have-lower-sars-cov-2-infection-rates-than-antibody-negative-healthcare-workers-large-multi-centre-prospective-cohort-study-the-siren-study-england-june-to-no\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,57],"topic":[31],"class_list":["post-3324","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-reinfection","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3324","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3324"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3324\/revisions"}],"predecessor-version":[{"id":3325,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3324\/revisions\/3325"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3324"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3324"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3324"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}