{"id":3473,"date":"2021-01-27T13:01:13","date_gmt":"2021-01-27T21:01:13","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3473"},"modified":"2021-01-28T13:02:56","modified_gmt":"2021-01-28T21:02:56","slug":"kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibo","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/27\/kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibo\/","title":{"rendered":"Kinetics and Correlates of the Neutralizing Antibody Response to SARS-CoV-2Kinetics and Correlates of the Neutralizing Antibody Response to SARS-CoV-2Kinetics and Correlates of the Neutralizing Antibody Response to SARS-CoV-2"},"content":{"rendered":"<p><i>[Pre-print, not per-reviewed]<\/i> A longitudinal study of people who had recovered from COVID-19 (n=963) estimated a half-life of 7.7 months for anti-spike IgG and a half-life of 8.7 months for serum neutralization, with only 13% of individuals losing seroreactivity at ten months. In addition, around 3% of recovered patients demonstrated effective cross-neutralizing IgG antibodies to SARS-CoV-1 without known prior exposure to the virus. Key factors in predicting the development of SARS-CoV-2 neutralizing activity in mild cases were seroreactivity, age, time since disease onset, and fever.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p><i>Vanshylla et al. (Jan 26, 2021). Kinetics and Correlates of the Neutralizing Antibody Response to SARS-CoV-2. Pre-print downloaded January 27 from <\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.01.26.428207\">https:\/\/doi.org\/10.1101\/2021.01.26.428207<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not per-reviewed] A longitudinal study of people who had recovered from COVID-19 (n=963) estimated a half-life of 7.7 months for anti-spike IgG and a half-life of 8.7 months for serum neutralization, with only 13% of individuals losing seroreactivity at ten months. In addition, around 3% of recovered patients demonstrated effective cross-neutralizing IgG antibodies to&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/27\/kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibody-response-to-sars-cov-2kinetics-and-correlates-of-the-neutralizing-antibo\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,32],"topic":[31],"class_list":["post-3473","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3473"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3473\/revisions"}],"predecessor-version":[{"id":3474,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3473\/revisions\/3474"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3473"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}