{"id":3487,"date":"2021-01-27T13:10:42","date_gmt":"2021-01-27T21:10:42","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3487"},"modified":"2021-01-28T13:13:23","modified_gmt":"2021-01-28T21:13:23","slug":"a-higher-bmi-is-not-associated-with-a-different-immune-response-and-disease-course-in-critically-ill-covid-19-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/27\/a-higher-bmi-is-not-associated-with-a-different-immune-response-and-disease-course-in-critically-ill-covid-19-patients\/","title":{"rendered":"A Higher BMI Is Not Associated with a Different Immune Response and Disease Course in Critically Ill COVID-19 Patients"},"content":{"rendered":"<p>Among patients with COVID-19 in The Netherlands who required mechanical ventilation in the ICU, higher BMI was not associated with differences in measurements of plasma cytokines or clinical outcomes. Patients (n=67) were classified as obese (BMI\u2009\u226530\u2009kg\/m<sup>2<\/sup>) and non-obese (BMI\u2009&lt;30\u2009kg\/m<sup>2<\/sup>). Obese participants had a lower elevation in body temperature (38.1C vs. 38.7C) but no other clinical differences between the groups were observed, including differences in time on ventilator, ICU length of stay, or 40-day mortality. BMI did not correlate with plasma levels of cytokines including IL-6, IL-8, TNF, MCP-1, IL-1RA, or IP-10.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p><i>Kooistra et al. (Jan 25, 2021). A Higher BMI Is Not Associated with a Different Immune Response and Disease Course in Critically Ill COVID-19 Patients. International Journal of Obesity. <\/i><a href=\"https:\/\/doi.org\/10.1038\/s41366-021-00747-z\">https:\/\/doi.org\/10.1038\/s41366-021-00747-z<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Among patients with COVID-19 in The Netherlands who required mechanical ventilation in the ICU, higher BMI was not associated with differences in measurements of plasma cytokines or clinical outcomes. Patients (n=67) were classified as obese (BMI\u2009\u226530\u2009kg\/m2) and non-obese (BMI\u2009&lt;30\u2009kg\/m2). Obese participants had a lower elevation in body temperature (38.1C vs. 38.7C) but no other clinical&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/01\/27\/a-higher-bmi-is-not-associated-with-a-different-immune-response-and-disease-course-in-critically-ill-covid-19-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[46],"topic":[20],"class_list":["post-3487","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-risk-factors","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3487"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3487\/revisions"}],"predecessor-version":[{"id":3488,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3487\/revisions\/3488"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3487"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3487"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3487"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}