{"id":3666,"date":"2021-02-03T22:16:46","date_gmt":"2021-02-04T06:16:46","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3666"},"modified":"2021-02-22T22:03:02","modified_gmt":"2021-02-23T06:03:02","slug":"neutralization-of-sars-cov-2-voc-501y-v2-by-human-antisera-elicited-by-both-inactivated-bbibp-corv-and-recombinant-dimeric-rbd-zf2001-vaccines","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/03\/neutralization-of-sars-cov-2-voc-501y-v2-by-human-antisera-elicited-by-both-inactivated-bbibp-corv-and-recombinant-dimeric-rbd-zf2001-vaccines\/","title":{"rendered":"Neutralization of SARS-CoV-2 VOC 501Y.V2 by Human Antisera Elicited by Both Inactivated BBIBP-CorV and Recombinant Dimeric RBD ZF2001 Vaccines"},"content":{"rendered":"<p><i>[Pre-print, not peer-reviewed]<\/i> Sera from 12 participants who received either the inactivated virus vaccine BBIP-CorV or the ZF2001 RBD protein subunit vaccine (both manufactured in China) showed neutralizing activity against the 501Y.V2 SARS-CoV-2 variant (first identified in South Africa). Neutralization was measured by microcytopathogenic effect assay and there were slightly reduced geometric mean antibody titers (about 1.6-fold for each vaccine) in the sera from participants vaccinated with either vaccine compared to those against the wild type D614G strain.<\/p>\n<p><i>Huang et al. (Feb 2, 2021). Neutralization of SARS-CoV-2 VOC 501Y.V2 by Human Antisera Elicited by Both Inactivated BBIBP-CorV and Recombinant Dimeric RBD ZF2001 Vaccines. BioRxiv. <\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.02.01.429069\">https:\/\/doi.org\/10.1101\/2021.02.01.429069<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Sera from 12 participants who received either the inactivated virus vaccine BBIP-CorV or the ZF2001 RBD protein subunit vaccine (both manufactured in China) showed neutralizing activity against the 501Y.V2 SARS-CoV-2 variant (first identified in South Africa). Neutralization was measured by microcytopathogenic effect assay and there were slightly reduced geometric mean antibody titers&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/03\/neutralization-of-sars-cov-2-voc-501y-v2-by-human-antisera-elicited-by-both-inactivated-bbibp-corv-and-recombinant-dimeric-rbd-zf2001-vaccines\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,33,159],"topic":[31],"class_list":["post-3666","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-vaccines","tag-variants","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3666","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3666"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3666\/revisions"}],"predecessor-version":[{"id":3667,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3666\/revisions\/3667"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3666"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3666"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3666"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}