{"id":3899,"date":"2021-02-13T11:50:37","date_gmt":"2021-02-13T19:50:37","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=3899"},"modified":"2021-02-13T11:50:37","modified_gmt":"2021-02-13T19:50:37","slug":"comparison-of-severe-acute-respiratory-syndrome-coronavirus-2-screening-using-reverse-transcriptase-quantitative-polymerase-chain-reaction-or-crispr-based-assays-in-asymptomatic-college-students","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/13\/comparison-of-severe-acute-respiratory-syndrome-coronavirus-2-screening-using-reverse-transcriptase-quantitative-polymerase-chain-reaction-or-crispr-based-assays-in-asymptomatic-college-students\/","title":{"rendered":"Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase-Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students"},"content":{"rendered":"<p>Rauch et al. concluded that CRISPR-based methods appear to offer reliable SARS-CoV-2 screening based on testing 1,808 asymptomatic college students with both RT-qPCR and CRISPR-based assays. Of the nine samples that tested positive by RT-PCR, eight were also positive by CRISPR-based assays, which are cheaper to run and use lab-generated or off-the-shelf reagents, potentially alleviating supply chain constraints.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p>The researchers also found that the viral loads detected in the asymptomatic cases resembled those seen in clinical samples, highlighting the potential for asymptomatic viral transmission.<\/p>\n<p><i>Rauch et al. (Feb 11, 2021). Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase-Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students. JAMA Network Open. <\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.37129\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.37129<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rauch et al. concluded that CRISPR-based methods appear to offer reliable SARS-CoV-2 screening based on testing 1,808 asymptomatic college students with both RT-qPCR and CRISPR-based assays. Of the nine samples that tested positive by RT-PCR, eight were also positive by CRISPR-based assays, which are cheaper to run and use lab-generated or off-the-shelf reagents, potentially alleviating&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/13\/comparison-of-severe-acute-respiratory-syndrome-coronavirus-2-screening-using-reverse-transcriptase-quantitative-polymerase-chain-reaction-or-crispr-based-assays-in-asymptomatic-college-students\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[172,73,27],"topic":[19],"class_list":["post-3899","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-brokendoi","tag-colleges","tag-testing","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=3899"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3899\/revisions"}],"predecessor-version":[{"id":3900,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/3899\/revisions\/3900"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=3899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=3899"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=3899"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=3899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}