{"id":4069,"date":"2020-02-06T16:27:05","date_gmt":"2020-02-07T00:27:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4069"},"modified":"2021-02-16T16:28:06","modified_gmt":"2021-02-17T00:28:06","slug":"clinical-evidence-does-not-support-corticosteroid-treatment-for-2019-ncov-lung-injury","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/06\/clinical-evidence-does-not-support-corticosteroid-treatment-for-2019-ncov-lung-injury\/","title":{"rendered":"Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Russell, <\/span><i><span style=\"font-weight: 400\">et al.<\/span><\/i><span style=\"font-weight: 400\"> review reasons not to use corticosteroids for treatment of 2019-nCoV, following WHO advice against their use in cases of novel coronavirus. Reasons are based on similarities in the biology and clinical presentation of 2019-nCoV, SARS, and MERS.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">An addition to other negative clinical outcomes described based on earlier studies, use of corticosteroid therapy in novel coronavirus patients likely delays clearance of viral RNA from respiratory secretions; and patients treated with corticosteroids were more likely to be viremic 2-3 weeks after treatment than persons given a saline control.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Russell, et al. (Feb 6, 2020).<\/span><\/i> <i><span style=\"font-weight: 400\">Clinical evidence does not support corticosteroid treatment<\/span><\/i><\/p>\n<p><i><span style=\"font-weight: 400\">for 2019-nCoV lung injury. The Lancet. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)30317-2\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/S0140-6736(20)30317-2<\/span><\/a><i><span style=\"font-weight: 400\">\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Russell, et al. review reasons not to use corticosteroids for treatment of 2019-nCoV, following WHO advice against their use in cases of novel coronavirus. Reasons are based on similarities in the biology and clinical presentation of 2019-nCoV, SARS, and MERS.\u00a0 An addition to other negative clinical outcomes described based on earlier studies, use of corticosteroid&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/06\/clinical-evidence-does-not-support-corticosteroid-treatment-for-2019-ncov-lung-injury\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-4069","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4069","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4069"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4069\/revisions"}],"predecessor-version":[{"id":4070,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4069\/revisions\/4070"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4069"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4069"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4069"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4069"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}