{"id":4071,"date":"2020-02-06T16:28:19","date_gmt":"2020-02-07T00:28:19","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4071"},"modified":"2021-02-16T16:29:49","modified_gmt":"2021-02-17T00:29:49","slug":"remdesivir-and-chloroquine-effectively-inhibit-the-recently-emerged-novel-coronavirus-2019-ncov-in-vitro","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/06\/remdesivir-and-chloroquine-effectively-inhibit-the-recently-emerged-novel-coronavirus-2019-ncov-in-vitro\/","title":{"rendered":"Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">In vitro <\/span><\/i><span style=\"font-weight: 400\">assessments of existing antivirals and selected other drugs found that remdesivir and chloroquine could be effective against 2019-nCoV. Remdeivir is noted as an inhibitor of viral reproduction that is already in clinical development for other severe viral illnesses (e.g., ebola and SARS), whereas chloroquine \u2013 a well-established antimalarial \u2013 might act by preventing viral entry into the host cell.\u00a0\u00a0\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Wang M, et al. (Feb 4, 2020). Remdesivir and chloroquine effectively inhibit the recently <\/span><\/i><i><span style=\"font-weight: 400\">emerged novel coronavirus (2019-nCoV) in vitro. Cell Research. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41422-020-0282-0\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1038\/s41422-020-0282-0<\/span><\/a><i><span style=\"font-weight: 400\">\u00a0 <\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In vitro assessments of existing antivirals and selected other drugs found that remdesivir and chloroquine could be effective against 2019-nCoV. Remdeivir is noted as an inhibitor of viral reproduction that is already in clinical development for other severe viral illnesses (e.g., ebola and SARS), whereas chloroquine \u2013 a well-established antimalarial \u2013 might act by preventing&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/06\/remdesivir-and-chloroquine-effectively-inhibit-the-recently-emerged-novel-coronavirus-2019-ncov-in-vitro\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-4071","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4071"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4071\/revisions"}],"predecessor-version":[{"id":4072,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4071\/revisions\/4072"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4071"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}