{"id":4097,"date":"2021-02-16T21:36:11","date_gmt":"2021-02-17T05:36:11","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4097"},"modified":"2021-02-16T21:36:11","modified_gmt":"2021-02-17T05:36:11","slug":"longitudinal-analysis-of-antibody-response-following-sars-cov-2-infection-in-pregnancy-from-the-first-trimester-to-delivery","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/16\/longitudinal-analysis-of-antibody-response-following-sars-cov-2-infection-in-pregnancy-from-the-first-trimester-to-delivery\/","title":{"rendered":"Longitudinal Analysis of Antibody Response Following SARS-CoV-2 Infection in Pregnancy: From the First Trimester to Delivery"},"content":{"rendered":"<p>In a cohort of 17 SARS-CoV-2 PCR-positive pregnant women followed from the end of the first trimester to delivery, IgG non-neutralizing antibodies (nNAbs) were detected in 71% (12 of 17), while neutralizing antibodies (NAbs) were detected in 53% of individuals (9 of the 12 who seroconverted with IgG nNAbs). Levels of NAbs remained stable throughout pregnancy. In contrast, nNAbs declined over the pregnancy, with a statistically significant decrease observed by week 16.<\/p>\n<p><i>Cosma et al. (Feb 2, 2021). Longitudinal Analysis of Antibody Response Following SARS-CoV-2 Infection in Pregnancy: From the First Trimester to Delivery. Journal of Reproductive Immunology. <\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jri.2021.103285\">https:\/\/doi.org\/10.1016\/j.jri.2021.103285<\/a><i><span class=\"Apple-converted-space\">\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a cohort of 17 SARS-CoV-2 PCR-positive pregnant women followed from the end of the first trimester to delivery, IgG non-neutralizing antibodies (nNAbs) were detected in 71% (12 of 17), while neutralizing antibodies (NAbs) were detected in 53% of individuals (9 of the 12 who seroconverted with IgG nNAbs). Levels of NAbs remained stable throughout&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/16\/longitudinal-analysis-of-antibody-response-following-sars-cov-2-infection-in-pregnancy-from-the-first-trimester-to-delivery\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,50],"topic":[31],"class_list":["post-4097","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-pregnancy","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4097"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4097\/revisions"}],"predecessor-version":[{"id":4098,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4097\/revisions\/4098"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4097"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}