{"id":4162,"date":"2020-02-10T14:53:05","date_gmt":"2020-02-10T22:53:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4162"},"modified":"2021-02-17T14:54:19","modified_gmt":"2021-02-17T22:54:19","slug":"clinical-characteristics-of-2019-novel-coronavirus-infection-in-china","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/10\/clinical-characteristics-of-2019-novel-coronavirus-infection-in-china\/","title":{"rendered":"Clinical characteristics of 2019 novel coronavirus infection in China"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Clinical characteristics of 1,099 laboratory-confirmed 2019-nCoV patients at 552 hospitals across China (through Jan 29) are described in relation to disease severity and a composite endpoint of ICU admission, mechanical ventilation, and death. Disease severity (including oxygen saturation, respiratory rate, blood leukocyte\/lymphocyte count, and chest X-ray\/CT manifestations) predicts clinical outcomes<\/span>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Median age of 47 years (only 9 cases below 15 years old)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">41.8% female<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">1.18% had direct contact with wildlife<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">31.3% had been to Wuhan; 71.8% had contact with someone who had been to Wuhan<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Symptoms: Fever (87.9%), cough (67.7%), fatigue (38.1%). Diarrhea, uncommon<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Median incubation period = 3 days (range 0-24)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">76.4% had various chest CT abnormalities<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">79.1% developed pneumonia<\/span>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Median time from symptom onset to pneumonia diagnosis 4 days (range 2-4)<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">1.4% had died at time of publication\u00a0<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Guan et al. (Feb 9, 2020). Clinical characteristics of 2019 novel coronavirus infection in China. Pre Print downloaded Feb 9 from <\/span><\/i><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.02.06.20020974v1\"><span style=\"font-weight: 400\">https:\/\/www.medrxiv.org\/content\/10.1101\/2020.02.06.20020974v1<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clinical characteristics of 1,099 laboratory-confirmed 2019-nCoV patients at 552 hospitals across China (through Jan 29) are described in relation to disease severity and a composite endpoint of ICU admission, mechanical ventilation, and death. Disease severity (including oxygen saturation, respiratory rate, blood leukocyte\/lymphocyte count, and chest X-ray\/CT manifestations) predicts clinical outcomes Median age of 47 years&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/10\/clinical-characteristics-of-2019-novel-coronavirus-infection-in-china\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-4162","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4162"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4162\/revisions"}],"predecessor-version":[{"id":4163,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4162\/revisions\/4163"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4162"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}