{"id":4178,"date":"2020-02-10T15:04:26","date_gmt":"2020-02-10T23:04:26","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4178"},"modified":"2021-02-17T15:05:28","modified_gmt":"2021-02-17T23:05:28","slug":"protein-structure-and-sequence-re-analysis-of-2019-ncov-genome-does-not-indicate-snakes-as-its-intermediate-host-or-the-unique-similarity-between-its-spike-protein-insertions-and-hiv-i","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/10\/protein-structure-and-sequence-re-analysis-of-2019-ncov-genome-does-not-indicate-snakes-as-its-intermediate-host-or-the-unique-similarity-between-its-spike-protein-insertions-and-hiv-i\/","title":{"rendered":"Protein structure and sequence re-analysis of 2019-nCoV genome does not indicate snakes as its intermediate host or the unique similarity between its spike protein insertions and HIV-I"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Researchers re-analyzed data reported in two prior papers that suggested snakes are an intermediary host for 2019-nCov. Their results do not support this conclusion, pointing instead to mammals and birds as more likely intermediary hosts. Findings also indicated that the previously reported \u201cunlikely\u201d similarity between a 2019-nCoV spike protein insertion and that of HIV-I was actually the result of natural evolution from bat coronaviruses.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Zhang et al. (Feb 8, 2020). Protein structure and sequence re-analysis of 2019-nCoV genome does not indicate snakes as its intermediate host or the unique similarity between its spike protein insertions and HIV-I. Pre Print downloaded Feb 10 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.02.04.933135\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.02.04.933135<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers re-analyzed data reported in two prior papers that suggested snakes are an intermediary host for 2019-nCov. Their results do not support this conclusion, pointing instead to mammals and birds as more likely intermediary hosts. Findings also indicated that the previously reported \u201cunlikely\u201d similarity between a 2019-nCoV spike protein insertion and that of HIV-I was&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/10\/protein-structure-and-sequence-re-analysis-of-2019-ncov-genome-does-not-indicate-snakes-as-its-intermediate-host-or-the-unique-similarity-between-its-spike-protein-insertions-and-hiv-i\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[178],"class_list":["post-4178","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-virology"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4178","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4178"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4178\/revisions"}],"predecessor-version":[{"id":4179,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4178\/revisions\/4179"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4178"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4178"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4178"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4178"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}