{"id":4325,"date":"2021-02-17T13:20:23","date_gmt":"2021-02-17T21:20:23","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4325"},"modified":"2021-02-18T13:42:51","modified_gmt":"2021-02-18T21:42:51","slug":"effect-of-a-single-high-dose-of-vitamin-d3-on-hospital-length-of-stay-in-patients-with-moderate-to-severe-covid-19-a-randomized-clinical-trial","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/17\/effect-of-a-single-high-dose-of-vitamin-d3-on-hospital-length-of-stay-in-patients-with-moderate-to-severe-covid-19-a-randomized-clinical-trial\/","title":{"rendered":"Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial"},"content":{"rendered":"<p>A randomized clinical trial involving 240 patients hospitalized with moderate to severe COVID-19 found that compared with placebo, a single dose (200,000 IU) of vitamin D<sub>3<\/sub> did not significantly reduce length of hospital stay (HR = 1.07). The difference between the vitamin D<sub>3<\/sub> group and the placebo group was not significant for in-hospital mortality (8% vs 5%), admission to the intensive care unit (16% vs 21%), or need for mechanical ventilation (8% vs 14%). No adverse events were recorded, but an episode of vomiting was associated with the intervention.<\/p>\n<p><i>Murai et al. (Feb 17, 2021). Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial. JAMA. <\/i><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2776738\">https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2776738<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A randomized clinical trial involving 240 patients hospitalized with moderate to severe COVID-19 found that compared with placebo, a single dose (200,000 IU) of vitamin D3 did not significantly reduce length of hospital stay (HR = 1.07). The difference between the vitamin D3 group and the placebo group was not significant for in-hospital mortality (8%&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/17\/effect-of-a-single-high-dose-of-vitamin-d3-on-hospital-length-of-stay-in-patients-with-moderate-to-severe-covid-19-a-randomized-clinical-trial\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-4325","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4325"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4325\/revisions"}],"predecessor-version":[{"id":4326,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4325\/revisions\/4326"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4325"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}