{"id":4391,"date":"2020-02-19T17:10:08","date_gmt":"2020-02-20T01:10:08","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4391"},"modified":"2021-02-18T17:11:03","modified_gmt":"2021-02-19T01:11:03","slug":"longitudinal-characteristics-of-lymphocyte-responses-and-cytokine-profiles-in-the-peripheral-blood-of-sars-cov-2-infected-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/19\/longitudinal-characteristics-of-lymphocyte-responses-and-cytokine-profiles-in-the-peripheral-blood-of-sars-cov-2-infected-patients\/","title":{"rendered":"Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Peripheral blood samples were collected longitudinally from 40 confirmed COVID-19 cases and evaluated for lymphocyte subsets and cytokine profiles. Severe cases had more sustained lymphocyte depletion but increased neutrophil counts compared to mild cases. T cell counts were also decreased among severe cases. The neutrophil-to-CD8+ T cell ratio may be a useful prognostic tool for early identification of severe COVID-19 cases.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Liu et al. (Feb 18, 2020). Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients. Pre-print downloaded Feb 19 from<\/span><\/i> <a href=\"https:\/\/doi.org\/10.1101\/2020.02.16.20023671\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.02.16.20023671<\/span><\/a><span style=\"font-weight: 400\">\u00a0\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Peripheral blood samples were collected longitudinally from 40 confirmed COVID-19 cases and evaluated for lymphocyte subsets and cytokine profiles. Severe cases had more sustained lymphocyte depletion but increased neutrophil counts compared to mild cases. T cell counts were also decreased among severe cases. The neutrophil-to-CD8+ T cell ratio may be a useful prognostic tool for&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/02\/19\/longitudinal-characteristics-of-lymphocyte-responses-and-cytokine-profiles-in-the-peripheral-blood-of-sars-cov-2-infected-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-4391","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4391"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4391\/revisions"}],"predecessor-version":[{"id":4392,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4391\/revisions\/4392"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4391"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}