{"id":4444,"date":"2021-02-18T19:49:25","date_gmt":"2021-02-19T03:49:25","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=4444"},"modified":"2021-02-19T19:50:28","modified_gmt":"2021-02-20T03:50:28","slug":"innate-cell-profiles-during-the-acute-and-convalescent-phase-of-sars-cov-2-infection-in-children","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/18\/innate-cell-profiles-during-the-acute-and-convalescent-phase-of-sars-cov-2-infection-in-children\/","title":{"rendered":"Innate Cell Profiles during the Acute and Convalescent Phase of SARS-CoV-2 Infection in Children"},"content":{"rendered":"<p>Cell profiles of children (n=48, aged &lt;18 years) with clinically mild SARS-CoV-2 were characterized by reduced circulating subsets of monocytes, dendritic cells, and natural killer cells during the acute phase of infection. In contrast, adults with SARS-CoV-2 infection (n=70) showed reduced proportions of non-classical monocytes only. Both children and adults who were exposed to SARS-CoV-2 but tested PCR negative had higher proportions of low-density neutrophils observed up to 7 weeks post exposure.<\/p>\n<p><i>Neeland et al.\u00a0(Feb 17, 2021). Innate Cell Profiles during the Acute and Convalescent Phase of SARS-CoV-2 Infection in Children. Nature Communications<\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33597531\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33597531\/<\/a><i><span class=\"Apple-converted-space\">\u00a0<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cell profiles of children (n=48, aged &lt;18 years) with clinically mild SARS-CoV-2 were characterized by reduced circulating subsets of monocytes, dendritic cells, and natural killer cells during the acute phase of infection. In contrast, adults with SARS-CoV-2 infection (n=70) showed reduced proportions of non-classical monocytes only. Both children and adults who were exposed to SARS-CoV-2&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/18\/innate-cell-profiles-during-the-acute-and-convalescent-phase-of-sars-cov-2-infection-in-children\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[41,34],"topic":[20],"class_list":["post-4444","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-children","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=4444"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4444\/revisions"}],"predecessor-version":[{"id":4445,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/4444\/revisions\/4445"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=4444"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=4444"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=4444"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=4444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}