{"id":5132,"date":"2021-02-25T20:45:29","date_gmt":"2021-02-26T04:45:29","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5132"},"modified":"2021-02-25T20:45:29","modified_gmt":"2021-02-26T04:45:29","slug":"association-of-sars-cov-2-seropositive-antibody-test-with-risk-of-future-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/25\/association-of-sars-cov-2-seropositive-antibody-test-with-risk-of-future-infection\/","title":{"rendered":"Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection"},"content":{"rendered":"<p>In a cohort study of over 3.2 million US patients with a SARS-CoV-2 antibody test result (88% negative), the ratio of seropositive to seronegative patients with a positive SARS-CoV-2 nucleic acid amplification test (NAAT) decreased from 3% within 30 days of the antibody test to 0.1% after at least 90 days following the antibody test. Among seropositive patients, 18% converted to seronegative over the follow-up period. The authors suggest that a higher likelihood of NAAT positivity among seropositive patients is consistent with prolonged viral RNA shedding, but that seroconversion may reduce future risk of SARS-CoV-2 infection.<\/p>\n<p><i>Harvey et al.\u00a0(Feb 24, 2021). Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection. JAMA Internal Medicine. <\/i><a href=\"https:\/\/doi.org\/10.1001\/jamainternmed.2021.0366\">https:\/\/doi.org\/10.1001\/jamainternmed.2021.0366<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a cohort study of over 3.2 million US patients with a SARS-CoV-2 antibody test result (88% negative), the ratio of seropositive to seronegative patients with a positive SARS-CoV-2 nucleic acid amplification test (NAAT) decreased from 3% within 30 days of the antibody test to 0.1% after at least 90 days following the antibody test&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/25\/association-of-sars-cov-2-seropositive-antibody-test-with-risk-of-future-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-5132","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5132"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5132\/revisions"}],"predecessor-version":[{"id":5133,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5132\/revisions\/5133"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5132"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}